famotidine, Pepcid, Pepcid AC

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Medical and Pharmacy Editor:

GENERIC NAME: famotidine

BRAND NAME: Pepcid, Pepcid AC, Acid Reducer, Heartburn Relief

DRUG CLASS AND MECHANISM: Famotidine is an oral drug that blocks the production of acid by acid-producing cells in the stomach. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes cimetidine (Tagamet), nizatidine (Axid), and ranitidine (Zantac). Histamine is a naturally-occurring chemical that stimulates cells in the stomach (parietal cells) to produce acid. H2-blockers inhibit the action of histamine on the cells, thus reducing the production of acid. Since excessive stomach acid can damage the esophagus, stomach, and duodenum and lead to inflammation and ulceration, reducing stomach acid prevents and heals acid-induced inflammation and ulcers. Famotidine was approved by the FDA in November 1986.

Medically Reviewed by a Doctor on 12/30/2014

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