Featured: ezetimibe and simvastatin, Vytorin Main Article

Vytorin is a cholesterol lowering drug. Vytorin is a combination of ezetimibe (Zetia) and simvastatin (Zocor). The simvastatin component of Vytorin is in a drug class called statins. Vytorin drug interactions include erythromycin, (E-Mycin), ketoconazole (Nizoral), itraconazole (Sporanox), clarithromycin (Biaxin), telithromycin (Ketek), cyclosporine (Sandimmune), nefazodone (Serzone), protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir) for HIV. Amiodarone (Cordarone), verapamil (Calan Verelan, Isoptin), danazol, niacin (Niacor, Niaspan, Slo-Niacin), gemfibrozil (Lopid) and fenofibrate (Tricor) warfarin (Coumadin), and digoxin (Lanoxin). Blood levels of simvastatin will increase when mixed with large quantities of grapefruit juice. This list is not all inclusive. Side effects include muscle pain, abnormal liver tests, headache, nausea, vomiting, diarrhea, and muscle pain.