ezetimibe, Zetia (cont.)

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Medical and Pharmacy Editor:

PRESCRIPTION: Yes

GENERIC AVAILABLE: No

PREPARATIONS: Tablets, 10 mg

STORAGE: Ezetimibe tablets should be stored between 15-30 C (59-86 F).

DOSING: The recommended dose of ezetimibe is 10 mg daily. Ezetimibe can be taken with or without food and at the same time as statin drugs.

DRUG INTERACTIONS: Cholestyramine (Questran), colestipol (Colestid) and colesevelam (WelChol), bile acid-binding drugs that may be used to treat elevated levels of cholesterol, bind to ezetimibe and reduce its absorption from the intestine by about 50%. Therefore, ezetimibe should be taken at least two hours before or 4 hours after administration of these drugs. Cyclosporine (Gengraf, Neoral) increases the levels of ezetimibe while ezetimibe increases levels of cyclosporine. Combining both drugs may increase side effects of either drug.

Medically Reviewed by a Doctor on 12/22/2015


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