Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: ezetimibe
BRAND NAME: Zetia
DRUG CLASS AND MECHANISM: Ezetimibe is an oral drug that is used for the treatment of elevated blood cholesterol. The most commonly used class of drugs for lowering cholesterol levels, the statins, act by preventing the production of cholesterol by the liver. Ezetimibe has a different mechanism of action and lowers blood cholesterol by reducing the absorption of cholesterol from the intestine. It does not affect the absorption of triglycerides or fat-soluble vitamins. The FDA approved ezetimibe in October 2002.
GENERIC AVAILABLE: No
PREPARATIONS: Tablets, 10 mg
STORAGE: Ezetimibe tablets should be stored between 15-30 C (59-86 F).
PRESCRIBED FOR: Ezetimibe is used alone or in combination with statins to improve levels of total cholesterol, low-density lipoprotein cholesterol, non-HDL cholesterol, and apolipoprotein B. Combining ezetimibe with a statin is more effective than either drug alone. Ezetimibe may be used alone or in combination with fibrates, for example, fenofibrate (Tricor), to improve levels of cholesterol, low-density lipoprotein cholesterol, and apolipoprotein B.
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