Eye Care (cont.)
What
inactive ingredients are contained in OTC eye-care products?
Most eye-care products contain ingredients that have no therapeutic value. If an
individual has a known sensitivity to one or more of these ingredients, then
products containing them should be avoided.
Vehicles:
An ophthalmic vehicle is added to a product to enhance drug action by
increasing the viscosity (thickness) of the product. Examples of ophthalmic
vehicles are Dextran 70, gelatin, glycerin, poloxamer 407, and propylene
glycol.
Preservatives:
Preservatives are included to destroy or limit growth of bacteria that may
be introduced into the product during repeated use. Examples of ophthalmic
preservatives are benzalkonium chloride (BAK), cetylpyridinium chloride,
chlorobutanol, methylparaben, sodium benzoate, and sorbic acid. To avoid
allergies, many ophthalmic products are preservative free.
Excipients:
An excipient is a substance that is added to provide physical form to the
product, make it less irritating to the eye, or to preserve the ingredients
within the product. Useful ophthalmic excipients are antioxidants, wetting
agents, buffers, and tonicity adjusters.
Reference: Harrison's
Principles of Internal Medicine, McGraw-Hill, edited by Eugene Braunwald, et al., 2001.
Last Editorial Review: 4/4/2008
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