What brand names are available for evolocumab?

Repatha

Is evolocumab available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for evolocumab?

Yes

What are the uses for evolocumab?

• Repatha is used along with diet, exercise and maximum tolerated doses of statins to reduce LDL cholesterol in adults with heterozygous familial hypercholesterolemia (and inherited disorder that causes high levels of LDL) or adults with heart problems related to excess cholesterol in the body.
• Repatha is also used along with diet and other LDL-lowering treatments, for example, statins, ezetimibe (Zetia) and LDL apheresis, to reduce cholesterol in people with homozygous familial hypercholesterolemia (an inherited disorder that causes high levels of LDL).

What are the side effects of evolocumab?

The most common side effects associated with Repatha treatment include

• injection site reactions,
• back pain,
• symptoms of the common cold, and
• flu-like symptoms.

Other side effects include

• diarrhea,
• muscle pain,
• muscle spasm,
• fatigue,
• urinary tract infections (UTIs),
• cough,
• allergic reactions,
• hypertension,
• headache,
• dizziness,
• joint pain,
• nausea,
• confusion, and
• pancreatitis

A more serious side effect is:

• Hypersensitivity reactions: Repatha should not be used in patients with a history of serious hypersensitivity reactions to the product. Hypersensitivity reactions include itching, rash, and hives, have occurred. Repatha should be discontinued if signs or symptoms of serious allergic reactions occur.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.