Premenstrual syndrome: Take 2 to 4 g by mouth once daily.
Rheumatoid arthritis: Take 540 mg to 2.8 g by mouth daily.
DRUG INTERACTIONS: Oenothera should be used with caution with medications that increase bruising and bleeding risks. Medications like aspirin, celecoxib (Celebrex), ibuprofen (Motrin), diclofenac (Voltaren), meloxicam (Mobic), naproxen (Aleve, Naprosyn), warfarin (Coumadin), enoxaparin (Lovenox), and clopidogrel (Plavix) should be used with caution with Oenothera.
PREGNANCY: There are no adequate studies of Oenothera use by pregnant women to determine its safety during pregnancy. It should be avoided by pregnant women.
NURSING MOTHERS: It is not known whether Oenothera enters breast milk.
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