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etoposide - injection, Toposar, Vepesid

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GENERIC NAME: ETOPOSIDE - INJECTION (ee-TOE-poe-side)

BRAND NAME(S): Toposar, Vepesid

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Severe lowering of blood counts (myelosuppression) may occur, which may cause infection or bleeding (sometimes fatal). Seek immediate medical attention if you develop symptoms of infection (fever, chills, persistent sore throat) or unusually easy bruising or bleeding (see also Side Effects section).

USES: Etoposide is used alone or in combination with other chemotherapies to treat testicular cancer that has not responded to other treatment and small cell lung cancer. Etoposide works by slowing cancer cell growth. It is also commonly known as VP-16.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat certain childhood cancers that have not responded to other treatment, certain types of leukemias, lymphomas, liver cancer, ovarian cancer, esophageal cancer, another type of lung cancer (non-small cell type), and a certain type of prostate cancer.

HOW TO USE: This medication is given by injection into a vein as directed by your doctor, over 30-60 minutes or longer to avoid lowering of blood pressure, which occurs when etoposide is given too quickly. The dosage is based on your medical condition and response to therapy.If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.Certain types of plastics (e.g., IV bags) have been known to crack or leak when undiluted etoposide is used. Consult your pharmacist for details.

SIDE EFFECTS: (see also Warning section)Nausea, vomiting, loss of appetite, strange aftertaste, diarrhea, mouth sores, muscle aches, drowsiness, fatigue, or skin color changes may occur. Nausea and vomiting can be quite severe. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Changes in diet such as eating several small meals or limiting activity may help decrease some of these effects. If these effects persist or worsen, notify your doctor or pharmacist promptly.Temporary hair loss may occur. Hair growth should return after treatment has ended.Etoposide, along with certain other anti-cancer drugs, has been known to cause acute leukemia. This is very rare. Consult your doctor for more details.Etoposide can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of an infection, such as fever, chills or persistent sore throat.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: tingling of hands or feet, yellowing of the eyes or skin, tarry or bloody stool, vision changes, abdominal pain, redness or swelling of your veins.A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, sweating, chest tightness, fast or irregular heartbeat, skin turning blue, cough, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Report Problems to the Food and Drug Administration   You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.