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- What is etodolac, and how does it work (mechanism of action)?
- Is etodolac available as a generic drug?
- Do I need a prescription for etodolac?
- What are the side effects of etodolac?
- What is the dosage for etodolac?
- Is etodolac safe to take if I'm pregnant or breastfeeding?
- What else should I know about etodolac?
What is etodolac, and how does it work (mechanism of action)?
Etodolac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin, Advil, Nuprin, etc.), naproxen (Aleve, Naprosyn), indomethacin (Indocin), nabumetone (Relafen) and numerous others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins which are chemicals that are responsible for pain and the fever and tenderness that often occur with inflammation. Etodolac blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. The FDA approved etodolac in January 1991.
Is etodolac available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for etodolac?
What are the side effects of etodolac?
The most common side effects from etodolac are:
- ringing in the ears,
- abdominal pain,
- fluid retention, and
- shortness of breath.
NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Etodolac also may cause stomach and intestinal bleeding and ulcers. Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Black, tarry stools, weakness, and dizziness upon standing may be the only signs of the bleeding. People who are allergic to other NSAIDs should not use etodolac. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients who already have impairment of kidney function or congestive heart failure, and treatment with NSAIDs in these patients should be done cautiously. Individuals with asthma are more likely to experience allergic reactions to etodolac and other NSAIDs.
Other important side effects of NSAIDs include:
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