GENERIC NAME: etodolac
DISCONTINUED BRAND: Lodine
DRUG CLASS AND MECHANISM: Etodolac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin, Advil, Nuprin, etc.), naproxen (Aleve, Naprosyn), indomethacin (Indocin), nabumetone (Relafen) and numerous others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins which are chemicals that are responsible for pain and the fever and tenderness that often occur with inflammation. Etodolac blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. The FDA approved etodolac in January 1991.
PRESCRIBED FOR: Etodolac is used for the treatment of inflammation and pain caused by osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. It also is used for treating soft tissue injuries, such as tendinitis and bursitis, and menstrual cramps.
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