eszopiclone, Lunesta (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
PRESCRIBED FOR: Eszopiclone is used for the treatment of insomnia characterized by difficulty falling asleep and/or difficulty maintaining sleep during the night and early morning.
SIDE EFFECTS: The most common side effects of eszopiclone are:
Eszopiclone is a controlled substance. Patients taking eszopiclone or any other sedative drug may become dependent on the drug for sleep and experience withdrawal symptoms when the drug is discontinued.
PREPARATIONS: Tablets of 1, 2, and 3 mg
STORAGE: Tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 F).
DOSING: The usual dose to improve or maintain sleep in most adults is 2 or 3 mg before bedtime. Persons over the age of 65 years usually are treated with 1 or 2 mg. Eszopiclone should be taken immediately before going to bed since the onset of sedation may occur as rapidly as 10 minutes. It should be taken only by individuals who intend to sleep for at least 8 hours since its effects may last up to six hours. A high fat meal reduces the absorption of eszopiclone and may reduce its effect.
DRUG INTERACTIONS: Alcohol (which causes sedation) and drugs that have sedating effects should not be used with eszopiclone since their sedating effects, when added to those of eszopiclone, may cause excessive sedation. Drugs that reduce the action of liver enzymes that break down eszopiclone (for example, ketoconazole [Nizoral, Extina, Zolegel, Kuric]) may increase blood levels of eszopiclone and its sedative effects.
PREGNANCY: Use of eszopiclone during pregnancy has not been adequately evaluated.
NURSING MOTHERS: It is not known whether eszopiclone is excreted in human breast milk. Because many medicines are excreted in breast milk and because the effect of eszopiclone on infants has not been studied, women should not breast feed while taking eszopiclone.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information
Medically Reviewed by a Doctor on 4/3/2015
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