GENERIC NAME: conjugated estrogens, synthetic
BRAND NAME: Cenestin
DRUG CLASS AND MECHANISM: Cenestin is a combination of nine estrogens. Estrogens are hormones produced by the ovaries that are necessary for the proper development of the female reproductive system and sexual characteristics. After menopause, there is a decrease in the amount of estrogen that is produced by the ovaries. This decrease in estrogen production is responsible for hot flashes, mood changes, sleep disturbance, decreased sexual function and other symptoms associated with menopause. Estrogen deficiency also has been linked to heart disease and bone loss (osteoporosis). Cenestin is similar to conjugated estrogens (Premarin), the other drug used for treating hot flashes. Unlike the estrogens in Premarin which are obtained from natural sources and blended to approximate the composition of estrogens found in urine of pregnant horses, the estrogens in Cenestin are synthetic (man- made) and are produced from plant material. Therefore, the estrogens in Cenestin are different from the estrogens found in Premarin. The FDA approved Cenestin in March 1999.
PRESCRIBED FOR: Cenestin is used for the relief of moderate to severe hot flashes and vulvar and vaginal atrophy due to estrogen deficiency resulting from menopause.
SIDE EFFECTS: Common side effects of conjugated estrogens are:
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