estrogens conjugated, Premarin (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Conjugated estrogens also are used for treating advanced prostate cancer in selected men and women with metastatic breast cancer. Although estrogens are approved for preventing osteoporosis, other non-estrogen medications are preferred for this purpose. Intravenous conjugated estrogens are used for treating abnormal uterine bleeding due to hormonal imbalance.

SIDE EFFECTS: Common side effects of conjugated estrogens are:

Other side important effects include:

  • vaginal spotting,
  • loss of periods or
  • excessively prolonged periods,
  • breast pain,
  • breast enlargement and
  • an increase or decrease in sexual drive.

Effects of estrogen on the skin include rash, and melasma (tan or brown patches) that may develop on the forehead, cheeks, or temples and may persist even after estrogens are stopped.

In the eyes, conjugated estrogens may cause an increase in the curvature of the cornea, and, as a result, patients with contact lenses may develop intolerance to their lenses.

Estrogens may increase calcium levels in the blood (hypercalcemia) in patients with breast and bone cancer.

Medically Reviewed by a Doctor on 1/29/2015

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