USES: This medication is a combination of hormones (estrogen and progestin) used to treat symptoms of menopause (e.g., hot flashes, vaginal dryness) and to prevent bone loss (osteoporosis) in people at high risk. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medications (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen/progestin HRT therapy for osteoporosis. If you have other medical conditions as well, and are prescribed estrogen/progestin HRT for more than one condition, consult your doctor about your treatment plan and its options.
HOW TO USE: Take this medication by mouth at the same time each day, usually once daily. It may be taken with food or immediately after a meal to prevent stomach upset. Do not increase your dose, take it more often than directed, or stop taking it without first consulting your doctor. Read the Patient Information Leaflet available from your pharmacist. Consult your doctor or pharmacist if you have any questions.
SIDE EFFECTS: Dizziness, lightheadedness, headache, stomach upset, bloating, irritability, changes in sleep patterns, fatigue, nausea, weight changes, increased/decreased interest in sex, and breast tenderness may occur. If any of these persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., severe depression, memory loss), calf pain/swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands and feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding or prolonged bleeding), unusual vaginal discharge/itching/odor, yellowing of the eyes or skin. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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