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ESTRADIOL/MEDROXYPROGESTERONE SUSPENSION-INJECTION, Lunelle (cont.)

PRECAUTIONS: Tell your doctor your medical history, especially of: tobacco (smoking) use, blood circulation problems (e.g., blood clots in the legs), stroke, heart disease, abnormal vaginal bleeding not diagnosed by your doctor, liver disease, cancer, high blood pressure, diabetes, headache problems (e.g., migraines), gallbladder disease, high cholesterol or triglyceride levels in your blood (e.g., blood lipids), eye problems or if you wear contact lenses, epilepsy, depression, any allergies. If you will be having surgery, be confined to a chair or bed for a long period of time (e.g., a long plane flight), or have recently delivered a baby, notify your doctor beforehand. Special precautions may need to be taken in these circumstances while you are taking this drug. This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: aminoglutethimide, anti-seizure medication (e.g., carbamazepine, phenobarbital, phenytoin), other hormones (e.g., estrogen, progesterone), antibiotics, rifampin, ascorbic acid (vitamin C), acetaminophen, St John's Wort, cyclosporine, prednisolone, theophylline, aspirin, anti-anxiety drugs (e.g., diazepam), morphine, clofibric acid. This drug may interfere with certain laboratory tests (e.g., folic acid, proteins, thyroid hormones). Do not start or stop any medicine without doctor or pharmacist approval.



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