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estradiol/norethindrone acetate patch - transdermal, Combipatch (cont.)

USES: This medication is used to reduce menopause symptoms. It helps reduce episodes of flushing and sweating of the upper body and face, commonly called hot flashes. It also helps treat dryness, itching, and burning around the vagina. These symptoms occur when a woman's body no longer makes the usual amount of female hormone (estrogen) such as in women after menopause and in young women who have had their ovaries removed or who have a condition called primary ovarian failure. This medication is a combination of 2 female hormones: an estrogen (estradiol) and a progestin (norethindrone). A progestin is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. A woman who has had her uterus removed does not need progestin and should not be treated with this combination medication.If you need treatment only for vaginal menopause symptoms (e.g., vaginal dryness), products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.Some estrogen products may also be used to prevent bone loss (osteoporosis) in people at high risk who cannot take non-estrogen drugs. There are several other medications (e.g., raloxifene, bisphosphonates such as alendronate) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen treatment.

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.This medication is for use on the skin only. Follow the dosing schedule carefully. Dosage is based on your medical condition and response to therapy.Apply the patch to a clean, smooth, dry, non-irritated area of the lower abdomen. Do not place the patch on the breast. Avoid the waistline since tight clothing may rub the patch off. Press firmly on the patch for at least 10 seconds to make sure it stays in place.Replace the patch with a new one, usually twice weekly (every 3 or 4 days) or as directed by your doctor. Be sure to remove the old patch. Do not wear more than one patch at a time. To avoid skin irritation, change to a different area on the lower abdomen with each new patch and do not apply to the same area for at least a week.The patch should be worn continuously, even while bathing. Do not expose the patch to the sun for long periods. If a patch falls off, you may reapply it to a different area on the lower abdomen. If the patch does not stick any longer, use a new one and continue your usual dosing schedule.Use this medication regularly to get the most benefit from it. To help you remember, change the patch on the same days each week. It may help to mark your calendar as a reminder.Inform your doctor if your condition does not improve or if it worsens.



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