Medications and Drugs

GENERIC NAME: ESTRADIOL - NORETHINDRONE ACETATE - TOPICAL PATCH (ess-truh-DYE-all/nor-ETH-in-drone)

BRAND NAME(S): Combipatch

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: This combination product is used for female hormone replacement therapy (HRT) in women who are no longer producing proper amounts (e.g., menopause/change of life). Combination HRT should not be used to prevent heart disease.

HOW TO USE: Use this product as prescribed. Follow the dosing schedule carefully. Dosage is based on your medical condition and response to therapy. Learn all the usage instructions in the product package insert and ask your doctor or pharmacist if you are unclear on any information. This medication should be used for the shortest possible length of time, so you obtain the benefits and minimize the chance of serious side effects from long-term treatment. Consult your doctor or pharmacist for details. Apply the patch to a clean, smooth, dry, non-irritated area of the lower abdomen. Do not place the patch on the breast and avoid the waistline since tight clothing may rub the patch off. Press firmly on the patch for at least 10 seconds to make sure it stays in place. To avoid skin irritation, rotate the site of application with each new patch. Each patch may be worn continually as prescribed even while showering or bathing. Do not wear more than one estradiol-norethindrone patch at a time. Do not allow the patch to be exposed to the sun for prolonged periods of time. Ask your pharmacist what to do if a patch starts to fall off.

SIDE EFFECTS: This product may cause nausea, loss of appetite, headache, bloating or skin irritation at the site of application. If these effects persist or worsen, notify your doctor promptly. Report promptly: painful menstrual periods, abnormal vaginal bleeding, vaginal discharge or irritation, breast pain, mental/mood changes (e.g., depression, memory loss). Very unlikely but report promptly: one-sided weakness, vision problems, slurred speech, leg pain, swelling, chest pain, trouble breathing, lumps in breast, stomach pain, joint pain. If you notice other effects not listed above, contact your doctor or pharmacist.