Adjuvant: The Latin "adjuvans" means to help, particularly to reach a goal.
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Atypical: Not typical, not usual, not normal, abnormal. Atypical is often used to refer to the appearance of precancerous or cancerous cells.
Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Birth control : Birth control is the use of any practices, methods, or devices to prevent pregnancy from occurring in a sexually active woman. Also referred to as family planning, pregnancy prevention, fertility control, or contraception; birth control methods are designed either to prevent fertilization of an egg or implantation of a fertilized egg in the uterus.
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Body mass index: A key index for relating a person's body weight to their height. The body mass index (BMI) is a person's weight in kilograms (kg) divided by their height in meters (m) squared.
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Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
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BRCA2: A gene that normally acts to restrain the growth of cells in the breast and ovary but which, when mutated, may predispose to breast cancer and to ovarian cancer . BRCA2 mutations have also been discovered to be responsible for a significant fraction of early-onset prostate cancer . The first breast cancer genes identified were BRCA1 and BRCA2. Mutations of BRCA1 and BRCA2 account for about half of all cases of inherited breast cancer. These tumors tend to occur in young women. BRCA1 and BRCA2 are usually not involved in breast cancer that is not hereditary.
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Breast cancer: Breast cancer is diagnosed with self- and physician-examination of the breasts, mammography, ultrasound testing, and biopsy. There are many types of breast cancer that differ in their capability of spreading to other body tissues (metastasis). Treatment of breast cancer depends on the type and location of the breast cancer, as well as the age and health of the patient. The American Cancer Society recommends that a woman should have a baseline mammogram between the ages of 35 and 40 years. Between 40 and 50 years of age mammograms are recommended every other year. After age 50 years, yearly mammograms are recommended.
Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast , colon, liver, lung, prostate, and stomach.
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Carcinoma in situ: Cancer that involves only the place in which it began and that has not spread. Carcinoma in situ is an early-stage tumor.
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Clinical trial: See: Clinical trials. See also: Inconclusive clinical trial; Negative clinical trial; Non-inferior clinical trial; Positive clinical trial.
DCIS: Ductal carcinoma in situ. A precancerous condition characterized by the clonal proliferation of malignant-looking cells in the lining of a breast duct without evidence of spread outside the duct to other tissues in the breast or outside the breast. DCIS is clearly the precursor (forerunner) of invasive breast cancer. This is evident from the sharing of clonal chromosome changes by DCIS and adjacent invasive cancers. In other words, invasive breast cancer evolves from DCIS. Also called intraductal carcinoma.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Endometrial cancer: Cancer of the womb (the uterus ). Endometrial cancer occurs most often in women between the ages of 55 and 70 years. It accounts for about 6% of cancer in women. Women at elevated risk for endometrial cancer include those who are obese , who have few or no children, who began menstruating at a young age, who had a late menopause , and women of high socioeconomic status. It is thought that most of these risk factors are related to hormones, especially excess estrogen .
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Genes: The basic biological units of heredity . Segments of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Hormone therapy: A form of treatment that takes advantage of the fact that certain cancers depend on hormones to grow. Hormone therapy may include giving hormones to the patient or decreasing the level of hormones in the body.
Hyperplasia: A condition in which there is an increase in the number of normal cells in a tissue or organ.
In situ: In the normal location. An "in situ" tumor is one that is confined to its site of origin and has not invaded neighboring tissue or gone elsewhere in the body.
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Indication: 1. In medicine, a condition which makes a particular treatment or procedure advisable. CML (chronic myeloid leukemia) is an indication for the use of Gleevec (imatinib mesylate). 2. A sign or a circumstance which points to or shows the cause, pathology, treatment, or outcome of an attack of disease. The presence of the Philadelphia chromosome in peripheral blood cells is an indication of a relapse in CML.
Last menstrual period: By convention, pregnancies are dated in weeks starting from the first day of a woman's last menstrual period (LMP). If her menstrual periods are regular and ovulation occurs on day 14 of her cycle, conception takes place about 2 weeks after her LMP. A woman is therefore considered to be 6 weeks pregnant 2 weeks after her first missed period.
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Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy, radiation, surgery, or medication, depending on the age of the patient and type of tumor.
Mammogram : An X-ray of the breast with the breast in a device that compresses and flattens it. There are two basic mammogram tests -- screening mammograms and diagnostic mammograms.
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Menarche: The time in a girl's life that menstruation first begins. During the menarche period, menstruation may be irregular and unpredictable. Mood, weight, activity level, and growth rate may fluctuate with the hormone levels as well. Synonymous with female puberty.
Menopause : The time in a woman's life when menstrual periods permanently stop; it is also called the "change of life." Menopause is the opposite of the menarche.
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Menstrual: Pertaining to menstruation (the menses), as in last menstrual period, menstrual cramps, menstrual cycle, and premenstrual syndrome. From the Latin menstrualis, from mensis meaning month.
Natural menopause : Natural menopause occurs when the ovaries naturally decrease their production of the sex hormones estrogen and progesterone; there are no menstrual periods for 12 consecutive months; and no other biological or physiological cause can account for this.
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Post-menopausal: See: Postmenopausal.
Postmenopausal: After the menopause . Postmenopausal is defined formally as the time after which a woman has experienced twelve (12) consecutive months of amenorrhea (lack of menstruation) without a period.
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Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation.
Risk factor: Something that increases a person's chances of developing a disease.
Therapy: The treatment of disease .
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- Breast Biopsy - Learn about the different types of breast biopsy procedures, which are used to remove suspicious breast growth and examined for the presence of cancer.
- Breast Cancer - Get the facts on breast cancer symptoms, signs, stages, types, research, risk factors, diagnosis, prevention information and treatment options: mastectomy, chemotherapy, radiation therapy.
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