esterified estrogens and methyltestosterone, Estratest, Estratest HS

Notice: Solvay Pharmaceuticals, Inc. announced on March 10, 2009, that it would discontinue supplying the marketplace with ESTRATEST® (Esterified Estrogens and Methyltestosterone) Tablets and ESTRATEST® HS (Esterified Estrogens and Methyltestosterone) Tablets. Effective March 31, 2009, the company will no longer accept orders for new product from its customers.

GENERIC NAME: esterified estrogens and methyltestosterone

BRAND NAME: Estratest

DRUG CLASS AND MECHANISM: Esterified estrogens are a mixture of related estrogens. Estrogens, when taken alone or in combination with a progestin, have been shown to reduce the risk for hip fracture due to osteoporosis by 25% as well as the risk of heart attack (myocardial infarction) and stroke by 40-50%. Esterified estrogens are used for numerous medical situations. Estrogens cause growth and development of female sex organs and the maintain sex characteristics, including growth of underarm and pubic hair and shaping of body contours and skeleton. Estrogens also increase secretions from the cervix and growth of the inner lining of the uterus (endometrium). Estrogens reduce LDL-cholesterol ("bad" cholesterol) and increase HDL-cholesterol ("good" cholesterol) concentrations.



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