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The Cleveland Clinic

Esophagitis

Esophagitis is an inflammation of the lining of the esophagus, the tube that carries food from the throat to the stomach. If left untreated, this condition can become very uncomfortable, causing problems with swallowing, ulcers, and scarring of the esophagus. In rare instances, a condition known as "Barrett's esophagus" may develop, which is a risk factor for esophageal cancer.

What Causes Esophagitis?

Esophagitis is caused by an infection or irritation in the esophagus. An infection can be caused by bacteria, viruses, fungi, or diseases that weaken the immune system. Infections that cause esophagitis include:

  • Candida. This is a yeast infection of the esophagus caused by the same fungus that causes vaginal yeast infections. The infection develops in the esophagus when the body's immune system is weak (such as in people with diabetes or HIV). It is usually very treatable with antifungal drugs.
  • Herpes. Like Candida, this viral infection can develop in the esophagus when the body's immune system is weak. It is treatable with antiviral drugs.

Irritation causing esophagitis may be caused by any of the following:

  • GERD, or gastroesophageal reflux disease
  • Vomiting
  • Surgery
  • Medications such as aspirin and other anti-inflammatory drugs
  • Taking a large pill with too little water or just before bedtime
  • Swallowing a toxic substance
  • Hernias
  • Radiation injury (after receiving radiation for cancer treatment)

What Are the Symptoms of Esophagitis?

Symptoms of esophagitis include:

  • Difficult and/or painful swallowing
  • Heartburn
  • Mouth sores
  • A feeling of something of being stuck in the throat
  • Nausea
  • Vomiting

If you have any of these symptoms, you should contact your health care provider as soon as possible.



Next: How Is Esophagitis Diagnosed? »

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  • Proton-Pump Inhibitors - Read about proton pump inhibitors (PPIs) prescribed for GERD, peptic ulcers, and h pylori. Examples of PPIs include Prilosec, Prevacid, Aciphex, Protonix, Nexium, and Zegarid.
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Esophagitis

What is GERD (acid reflux)?

Gastroesophageal reflux disease, commonly referred to as GERD or acid reflux, is a condition in which the liquid content of the stomach regurgitates (backs up or refluxes) into the esophagus. The liquid can inflame and damage the lining (cause, cause esophagitis) of the esophagus although visible signs of inflammation occur in a minority of patients. The regurgitated liquid usually contains acid and pepsin that are produced by the stomach. (Pepsin is an enzyme that begins the digestion of proteins in the stomach.) The refluxed liquid also may contain bile that has backed-up into the stomach from the duodenum. (The duodenum is the first part of the small intestine that attaches to the stomach.) Acid is believed to be the most injurious component of the refluxed liquid. Pepsin and bile also may injure the esophagus, but their role in the production of esophageal inflammation and damage is not as clear as the role of acid.

GERD is a chronic c...

Read the Gastroesophageal Reflux Disease (GERD, Heartburn) article »










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