Esophageal Manometry (cont.)

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How is esophageal manometry used to assist in the diagnosis of diseases and conditions?

The esophagus is a muscular tube that connects the throat with the stomach. When food is propelled by a swallow from the mouth into the esophagus, a wave of muscular contraction starts behind the food in the upper esophagus and travels down the entire length of the esophagus (referred to as the body of the esophagus), thus propelling the food in front of the wave through the esophagus and into the stomach. At the upper and lower ends of the esophagus are two short areas of specialized muscle called the upper and lower esophageal sphincters. At rest (that is, when there has been no swallow) the muscle of the sphincters is active and generates pressure that prevents anything from passing through them. As a result, material within the esophagus cannot back up into the throat, and stomach acid and contents cannot back up into the esophagus. When a swallow occurs, both the sphincters relax for a few seconds to allow food to pass through the esophagus into the stomach.

The most common use for esophageal manometry is to evaluate the lower esophageal sphincter and the muscle of the body of the esophagus in patients who have gastroesophageal reflux disease (GERD). Manometry often can identify weakness in the lower esophageal sphincter that allows stomach acid and contents to back up into the esophagus. It also may identify abnormalities in the functioning of the muscle of the esophageal body that may add to the problem of reflux.

Manometry can help diagnose several esophageal conditions that result in food sticking after it is swallowed. For example, achalasia is a condition in which the muscle of the lower esophageal sphincter does not relax completely with each swallow. As a result, food is trapped within the esophagus. Abnormal function of the muscle of the body of the esophagus also may result in food sticking. For instance, there may be failure to develop the wave of muscular contraction (as can occur in patients with scleroderma) or the entire esophageal muscle may contract at one time (as in an esophageal spasm). Manometry reveals an absence of the wave in the first case and the contraction of the muscle everywhere in the esophagus at the same time, or spasm, in the second case.

The abnormal functioning of the esophageal muscle also may cause episodes of severe chest pain that can mimic heart pain (angina). Such pain may occur if the esophageal muscle goes into spasm or contracts too strongly. In either case, esophageal manometry may identify the muscular abnormality.

Medically Reviewed by a Doctor on 2/4/2014

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