esmolol hydrochloride-injection, Brevibloc (cont.)

SIDE EFFECTS: Nausea and drowsiness may occur. If these effects persist or worsen, notify your doctor. Report promptly any: dizziness, sweating, pain/redness at the injection site. Unlikely but report promptly: mental/mood changes, headache, rash. Very unlikely but report promptly: chest pain, swelling, trouble breathing, unusually slow or irregular pulse, changes in skin color, fainting, seizures. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, including: any allergies, heart disease, kidney disease, low blood pressure (hypotension), breathing problems (asthma or COPD), diabetes. Limit alcohol intake, as this may intensify drug side effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all nonprescription and prescription medication you may use, especially: other beta-blockers (e.g., propranolol, metoprolol), "calcium channel blockers" (e.g., verapamil, diltiazem, nifedipine), digoxin, morphine, NSAIDs (e.g., ibuprofen), arbutamine, dopamine, succinylcholine, epinephrine/norepinephrine, other blood pressure medicine (e.g., reserpine, clonidine), "blood thinners" (e.g., warfarin), St John's wort. This drug can block some effects of adrenaline (epinephrine), which is a drug used to treat allergic emergencies. Consult your doctor. Also report use of drugs causing drowsiness such as: antidepressants (e.g., amitriptyline, fluoxetine, sertraline), sedatives, tranquilizers, narcotic pain relievers (e.g., codeine), certain antihistamines (e.g., diphenhydramine). Do not mix this drug with sodium bicarbonate IV fluids. Do not start or stop any medicine without doctor or pharmacist approval.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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