erythromycin/sulfisoxazole suspension - oral, Pediazole

PRECAUTIONS: Before taking erythromycin with sulfisoxazole, tell the doctor or pharmacist if your child is allergic to it; or to other macrolide antibiotics (such as azithromycin, clarithromycin) or sulfa medications; or if your child has any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your child's pharmacist for more details.Before using this medication, tell the doctor or pharmacist your child's medical history, especially of: severe allergies, asthma, blood disorders (such as porphyria, bone marrow suppression/low blood cell counts), a certain genetic condition (glucose-6-phosphate dehydrogenase/G6PD deficiency), kidney disease, liver disease, a certain type of muscle disease (myasthenia gravis).Erythromycin/sulfisoxazole may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.The risk of QT prolongation may be increased if your child has certain medical conditions or is taking other drugs that may cause QT prolongation. Before using erythromycin/sulfisoxazole, tell the doctor or pharmacist of all the drugs your child takes and if your child has any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).Low levels of potassium or magnesium in the blood may also increase your child's risk of QT prolongation. This risk may increase if your child uses certain drugs (such as diuretics/"water pills") or if your child has conditions such as severe sweating, diarrhea, or vomiting. Talk to the doctor about using erythromycin/sulfisoxazole safely.This medication may make your child more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Have your child use a sunscreen and wear protective clothing when outdoors.Erythromycin/sulfisoxazole may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. Therefore, do not have any immunizations/vaccinations while using this medication without the consent of your child's doctor.Before having surgery, tell your child's doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially hearing loss and QT prolongation (see above).Infants may be more sensitive to the side effects of this drug, especially a stomach problem called IHPS (infantile hypertrophic pyloric stenosis). Contact your child's doctor immediately if your child has persistent vomiting or increased irritability with feeding.During pregnancy, this medication should be used only when clearly needed. This medication must not be used near the time of delivery because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor.This medication passes into breast milk. It may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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