erythromycin and benzoyl peroxide (gel or pak), Benzamycin
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: erythromycin and benzoyl peroxide (gel or pak)
BRAND NAME: Benzamycin
DRUG CLASS AND MECHANISM: Benzamycin is a combination of erythromycin and benzoyl peroxide and is used for the topical treatment of acne (pimples). Erythromycin is an antibiotic. The exact mechanism by which topical erythromycin reduces pimples is unknown. Erythromycin probably reduces pimples by penetrating into the skin and killing bacteria that contribute to the formation of pimples. Benzoyl peroxide works through several mechanisms. It kills the bacteria and promotes the growth of new skin cells. It also dries the skin. Increased cell growth leads to replacement of the pimples with new skin. Combining erythromycin and benzoyl peroxide is more convenient than using them separately. The FDA approved Benzamycin in November 2000.
GENERIC AVAILABLE: Yes
PREPARATIONS: Benzamycin is dispensed in amounts of 46.6 gm containing 1.6 grams of erythromycin powder and 40 grams of benzoyl peroxide gel. The erythromycin powder is mixed with 6 ml of ethyl alcohol and then added to the benzoyl peroxide gel before it is dispensed to the patient. Benzamycin also is available as Benzamycin Pak, 60 individual-use packets containing both erythromycin and benzoyl peroxide as gels in separate compartment within the packet. Just prior to use, the packet is opened, and the gels are mixed.
STORAGE: Prior to mixing the erythromycin and benzoyl peroxide together, Benzamycin should be stored at room temperature, 15-30 C (59-86 F). After mixing, Benzamycin should be stored in the refrigerator between 2 -8 C (36–46 F) and discarded after 3 months.
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