erlotinib, Tarceva (cont.)

Pharmacy Author:
Medical Editor:



PREPARATIONS: Tablets: 25, 100, and 150 mg

STORAGE: Erlotinib should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

DOSING: The usual dose of erlotinib is 150 mg daily for NSCLC and 100 mg daily for pancreatic cancer. Erlotinib should be taken on an empty stomach at least one hour before or two hours after eating because food may reduce the absorption of erlotinib.

DRUG INTERACTIONS: CYP3A4 is an enzyme in the liver that breaks-down and helps to eliminate erlotinib from the body. Drugs that inhibit CYP3A4 can result in high levels of erlotinib in the body, and the high levels can result in toxicity from erlotinib. Such drugs include atazanavir (Reyataz), clarithromycin (Biaxin), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), nefazodone (Serzone), nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase; Fortovase), telithromycin (Ketek), and voriconazole (VFEND). In patients receiving these drugs, a lower dose of erlotinib may be needed to prevent toxicity.

Medically Reviewed by a Doctor on 7/21/2015

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index