ergotamine-belladonna-phenobarbital-oral tablet (cont.)
DRUG INTERACTIONS: Infrequently, a very serious, life-threatening decrease in the amount of blood supply to the hands and feet (peripheral ischemia) and rarely to the brain can occur when this medication is taken with drugs that affect liver metabolism (e.g., potent CYP 3A4 enzyme inhibitors). Do not take this medication with macrolide antibiotics (e.g., erythromycin, clarithromycin, troleandomycin), HIV protease inhibitors (e.g., ritonavir, nelfinavir, indinavir, amprenavir, saquinavir), azole antifungals (e.g., ketoconazole, itraconazole). Tell your doctor of all prescription and nonprescription medications you may use, especially of: digoxin, cyclosporine, saquinavir, ritonavir, sleep medicines, "triptan" drugs (e.g., sumatriptan), beta-blockers (e.g., propranolol), St John's wort, nefazodone, fluconazole, fluoxetine, fluvoxamine, zileuton, clotrimazole, other mild CYP 3A4 enzyme inhibitors. Tell your doctor if you take any drugs that make you drowsy, such as: tricyclic antidepressants (e.g., amitriptyline), narcotic pain relievers (e.g., codeine), tranquilizers, certain antihistamines found in cold medicines (e.g., diphenhydramine). Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. This drug may interfere with the effectiveness of birth control pills. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include blurred vision, dilated pupils, hot and dry skin, dizziness, dryness of mouth, and slow or shallow breathing.
NOTES: Do not share this medication with others.
MISSED DOSE: If you miss a dose, take it as soon as remembered; do not take it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Do not store in the bathroom.
Last Editorial Review: 3/2/2005
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