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epirubicin hydrochloride-injection (cont.)

SIDE EFFECTS: Nausea, hair loss, diarrhea, or stomach pain may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. This medication may cause your urine to turn red in color. This is a normal effect of the drug. It is temporary and should disappear in one to two days. Notify your doctor if this effect persists longer than two days. Tell your doctor immediately if any of these serious side effects occur: pain or redness at the injection site, easy bruising or bleeding, persistent sore throat or fever, unusual tiredness, flushing, changes in menstrual period, eye problems, sores in the mouth or throat. Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/slow/irregular heartbeat, unexplained weight gain, bloating, loss of appetite, joint pain, sun sensitivity, chest pain, changes in the appearance of the skin. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking epirubicin, tell your doctor or pharmacist if you are allergic to it; or to athracyclines such as daunorubicin or doxorubicin, or to anthracenediones such as mitoxantrone; or if you have any other allergies. This medication is not recommended for use if you have any of the following medical conditions: bone marrow suppression (e.g., leukopenia, neutropenia), heart problems (e.g., congestive heart failure, myocardial infarction), liver problems. Tell your doctor your medical history, especially of: previous chemotherapy or radiation treatments, kidney problems. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, use a sunscreen, and wear protective clothing when outdoors. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects. Caution is advised when using this drug in children because they may be more sensitive to its effects. Because this medication may effect the production of sperm, it is recommended that men undergoing treatment with this drug use effective contraceptive methods (e.g., condoms). Consult your doctor or pharmacist for details. This medication can interfere with the menstrual cycle and cause premature menopause (change of life). Consult your doctor or pharmacist for details. This medication is not recommended for use during pregnancy. Consult your doctor for more details. Based on information of related drugs, this medication may pass into breast milk. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast- feeding.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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