epinephrine injection (Auvi-Q)

  • Medical Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

  • Pharmacy Author: Omudhome Ogbru, PharmD
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

What is epinephrine injection Auvi-Q, and how does it work (mechanism of action)?

Auvi-Q is an auto-injectable epinephrine-containing device used for self-administration during life-threatening allergic reactions, including anaphylaxis. Auvi-Q is an epinephrine auto-injector that talks the user step by step through the injection process. Epinephrine, the medicine contained in Auvi-Q, is an excitatory chemical naturally made by our bodies. Epinephrine stimulates alpha and beta adrenergic receptors found throughout the body. When injected during an allergic reaction, epinephrine works in multiple ways to treat the many signs of anaphylaxis. It causes blood vessels to constrict or tighten which helps to increase blood pressure and decrease swelling. Epinephrine also stimulates the heart muscle, causing the heart to beat faster and pump more blood to the vital organs. Epinephrine helps patient's breathe better by relaxing the muscles in the lungs and allowing the airways to open up. Additionally, it also helps to prevent further release of inflammatory chemicals that were triggered by the initial allergic reaction.

Auvi-Q was approved by the FDA in 2012.

What brand names are available for epinephrine injection Auvi-Q?

Auvi-Q

Is epinephrine injection Auvi-Q available as a generic drug?

GENERIC AVAILABLE: Although auto-injectable epinephrine is available in generic forms, a generic version of Auvi-Q device is currently not available.

Do I need a prescription for epinephrine injection Auvi-Q?

Yes

What are the side effects of epinephrine injection Auvi-Q?

The most common side effects of Auvi-Q include:

Auvi-Q is intended for administration in the muscle or fat tissues in the outer thigh only. Injecting Auvi-Q in other areas of the body including the buttocks, hands, or feet may not provide effective treatment of anaphylaxis and may even cause side effects.

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