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February 10, 2012
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epinephrine auto-injector, Epipen, Twinject (cont.)

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This product may contain sulfites. However, if you have a sulfite allergy, this should not be a reason for avoiding use of this medication during an emergency. Since epinephrine can be life-saving, using it is more important than avoiding any sulfite-related problems you may experience.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart conditions (e.g., coronary artery disease, arrhythmias), high blood pressure, thyroid disease, diabetes.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.The elderly may be more sensitive to the effects of this drug, especially a rapid rise in blood pressure, with increased risk if they also have heart disease.This medication should be used only if clearly needed during pregnancy or breast-feeding. Discuss the risks and benefits with your doctor.

DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and will monitor you for them after you receive epinephrine. Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anti-arrhythmic drugs (e.g., amiodarone, quinidine), beta-blockers (e.g., propranolol), digoxin, entacapone, ergot alkaloids (e.g., ergotamine), MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), phenothiazines (e.g., chlorpromazine), thyroid hormones (e.g., levothyroxine), tricyclic antidepressants (e.g., amitriptyline, doxepin), "water pills" (diuretics such as furosemide, hydrochlorothiazide).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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