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The Cleveland Clinic

Epilepsy: Treating Epilepsy

How Is Epilepsy Treated?

The majority of epileptic seizures are controlled through drug therapy, particularly anticonvulsant drugs. The type of treatment prescribed will depend on several factors including the frequency and severity of the seizures as well as the person's age, overall health and medical history. An accurate diagnosis of the type of epilepsy (not just the type of seizure, since most seizure types occur in different types of epilepsy) is also critical to choosing the best treatment.

Drug Therapy

Many drugs are available to treat epilepsy, several of which have only recently been released.

Older, classic medications used to treat epilepsy include:

  • Dilantin or Phenytek
  • Phenobarbital
  • Tegretol or Carbatrol
  • Mysoline
  • Zarontin
  • Depakene
  • Depakote, Depakote ER
  • Valium and similar tranquilizers such as Tranxene and Klonopin

Newer drugs to treat epilepsy include:

  • Felbatol
  • Gabitril
  • Keppra
  • Lamictal
  • Neurontin
  • Topamax
  • Trileptal
  • Zonegran

Many other drugs are being studied, including Lyrica, which will likely be the next anti-epileptic drug released in the U.S.

In general, for a given type of epilepsy there are only minor differences among appropriate drugs. The choice is most often based on other factors specific to each patient, such as which side effects can be tolerated by the patient, other illnesses they may have, and which delivery method is acceptable.

Although the different types of epilepsy vary greatly, in general, medications can control seizures in about 70% of patients.



Next: Side effects of epilepsy treatment »

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Generalized seizures

There are six types of generalized seizures. The most common and dramatic, and therefore the most well known, is the generalized convulsion, also called the grand-mal seizure. In this type of seizure, the patient loses consciousness and usually collapses. The loss of consciousness is followed by generalized body stiffening (called the "tonic" phase of the seizure) for 30 to 60 seconds, then by violent jerking (the "clonic" phase) for 30 to 60 seconds, after which the patient goes into a deep sleep (the "postictal" or after-seizure phase). During grand-mal seizures, injuries and accidents may occur, such as tongue biting and urinary incontinence.

Absence seizures cause a short loss of consciousness (just a few seconds) with few or no symptoms. The patient, most often a child, typically interrupts an activity and stares blankly. These seizures begin and end abruptly and may occur several times a day. Patients are usu...

Read the Seizures Symptoms and Types article »











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