Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
Eosinophils are a particular type of white blood
cells, usually representing a small percentage (less than 8% of
the total white blood cell population) that are easily stained by eosin and other dyes; they have a characteristic double-lobed nucleus. The number
of these cells (eosinophil count) increases in certain illnesses, including allergies,
asthma, Addison's disease, sarcoidosis, parasite infections, drug
reactions, and connective tissue diseases (such as rheumatoid
arthritis and scleroderma).
What is fascia?
The fascia is a sheet or band of fibrous connective tissue under the skin that covers a surface of underlying tissues. Fascia surrounds each of the muscles that move the skeleton. When the fascia is inflamed, the condition is referred to as "fasciitis."
What is eosinophilic fasciitis?
Eosinophilic fasciitis is a rare disease that leads to
inflammation and thickening of the skin and fascia underneath.
In patients with eosinophilic fasciitis, the involved fascia is
inflamed with the eosinophil type of white blood cells. This leads to symptoms of
progressive thickening and often redness, warmth, and hardness
of the skin surface.
Occasionally, the onset of eosinophilic fasciitis follows a period of exertional physical activity. Eosinophilic fasciitis
is sometimes confused with eosinophilia-myalgia
syndrome and scleroderma. Eosinophilic fasciitis sometimes occurs associated with cancers such as leukemia and lymphoma.
Scleroderma is a disease of the connective tissue featuring skin thickening, that can involve scarring, blood vessel problems, varying degrees of inflammation, and is associated with an overactive imm"...