enoxaparin, Lovenox (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Enoxaparin is used for preventing deep vein thrombosis after abdominal, hip replacement, or knee replacement surgeries, and in patients with reduced mobility due to illness. It is used both in and out of the hospital for treating deep vein thrombosis and pulmonary embolism. Enoxaparin also is used for preventing a second heart attack and related complications after a heart attack and for preventing blood clots in arterial stents.

SIDE EFFECTS:Common side effect associated with enoxaparin are:

Other important side effects are:

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Enoxaparin is available in pre-filled syringes containing 30, 40, 60, 80, 100, 120, and 150 mg. Multiple dose vial: 300 mg STORAGE: All enoxaparin products should be stored at room temperature, between 15 and 30 C (59-86 F).

DOSING: Enoxaparin is administered by injection under the skin (subcutaneous) or intravenously.

  • Preventing deep vein thrombosis after abdominal surgery: 40 mg subcutaneous injection once daily.
  • Preventing deep vein thrombosis after knee replacement: 30 mg subcutaneous injection every 12 hours.
  • Preventing deep vein thrombosis after hip replacement: 30 mg every 12 hours or 40 mg once daily by subcutaneous injection.
  • Preventing deep vein thrombosis in ill patients with limited mobility: 40 mg subcutaneous injection once daily.
  • Treatment of deep vein thrombosis or pulmonary embolism: 1 mg/kg every 12 hours or 1.5 mg/kg once daily by subcutaneous injection.
  • Outpatient treatment of deep vein thrombosis: 1 mg/kg subcutaneous injection every 12 hours.
  • Treatment of severe heart attacks (ST elevation myocardial infarction or STEMI): For patients under the age of 75, 30 mg intravenously plus 1 mg/kg subcutaneously followed by 1 mg/kg every 12 hours (maximum of 100 mg for each of the first two subcutaneous doses only). For patients over age 75, 0.75 mg/kg subcutaneously every 12 hours (maximum of 75 mg for each of the first two subcutaneous doses only). All patients should receive aspirin. Doses should be reduced in patients with impaired kidney function.
  • Treatment of chest pain (unstable angina) or mild heart attack (non-Q-wave myocardial infarction): 1 mg/kg subcutaneously every 12 hours with aspirin.
  • For coronary artery stent procedures (percutaneous coronary intervention or PCI): Patients should receive 0.3 mg/kg during stent placement if the last dose of enoxaparin was administered more than 8 hours before the procedure.
Medically Reviewed by a Doctor on 12/10/2014


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