Patient Comments: Enlarged Spleen - Cause

What caused your case of an enlarged spleen?

A Doctor's View on Enlarged Spleen (Splenomegaly) Causes

Read the Comment by John P. Cunha, DO, FACOEP

The spleen helps your body fight bacteria and infections. Diseases and conditions cause the spleen to become enlarged. Some of the common causes that may enlarge your spleen are liver disease, cancers, infections, inflammation of the heart. Read the entire Doctor's View

Comment from: Jason, 45-54 Male (Patient) Published: February 02

I have PV (polycythemia vera) cancer. My body makes too much blood and my spleen is 3 times larger than it should be. It is very rare but a bone marrow biopsy is the only way to find out.

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Comment from: JoHL, 45-54 Female (Patient) Published: October 01

I have a history of iron deficiency anemia as a child. I was hemolytic when suffering from the usual children's illnesses like tonsillitis. I had glandular fever at 21. Usual blood tests done at that time but an observant person looking at my tests for iron deficiency realized there were lots of spherocytes present in my blood sample. Hemoglobin was 6. Reticulocyte count was 584. Glandular fever lasted 6 months and symptoms returned 1 year later. My enlarged spleen is a result of congenital spherocytosis (hemolytic anemia). I wasn't diagnosed until I was 25 despite a history of all the relevant symptoms throughout my childhood.

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Comment from: Spleeno, 35-44 Male (Patient) Published: June 12

I have an enlarged spleen for 4 months. Many doctors can't figure out why. It's very painful in the left side and upper abdomen. I have had bladder and urinary pain too, but all tests are normal. I feel like I'm dying.

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Comment from: Toy Story, 35-44 Male (Patient) Published: April 07

I have portal hypertension and an enlarged spleen due to treatment for cancer when I was young. I have low counts on all my blood results. It makes me feel tired, I am prone to infection, and feel generally unwell.

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Comment from: Mr. K, 55-64 Male (Patient) Published: April 07

Crohn's disease, Type 2 Diabetic, Liver Transplant recipient, appendix and Gall Bladder removed. Enlarge Spleen, anemic, loss of appetite resulting in 30 pound loss in the last 2 months. Occasional night Sweats.

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Comment from: 19-24 Male (Patient) Published: April 07

My spleen is enlarged due to Typhi H infection. I have a very low level of energy all day. The symptoms are painful and indescribable.

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Comment from: Painful & Lethargic, 25-34 Female (Patient) Published: March 08

My enlarged spleen is the result of a mononucleosis (Epstein Barr) infection. I am 29 years old, and was unaware that mono was such a threat to people outside of their teens and early twenties. I currently work in the medical field and suspect that I acquired the virus as a result of my occupation. I have not been drinking after others or kissing! Hoping my spleen (and energy level) returns to normal soon!

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Comment from: kiwisrock, 45-54 (Patient) Published: April 07

My enlarged spleen is the result of cirrhosis of the liver which has occurred from the pain medicines I take for a shoulder injury I got at work 4 years ago. My spleen measures roughly 21cm, and with that and my enlarged liver, I look about 9 months pregnant, I have to lose weight and hopefully that will reverse some of the symptoms.

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