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There isn't enough information to know if English ivy is safe to apply directly to the skin. Fresh leaves can irritate the skin.
Special Precautions & Warnings:Pregnancy and breast-feeding: Not enough is known about the use of English ivy during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.