Patient Comments: Endometrial Biopsy - Experience

Have you had an endometrial biopsy? Please describe your experience.

Comment from: Tress, 55-64 Female (Patient) Published: September 19

Well, I am a first timer of endometrial biopsy, no prior understanding of procedure. They had to clamp a 'jumpy uterus', still okay, but then, during the second tissue collection, there was a moment of 'no way!' Just like the line crossed, when giving birth, there was intense pain. It was afterwards that one is not prepared too. Similar to my stereotactic breast biopsy, where you roll over, catch a good breath and weep. To be a woman!

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Comment from: Callie, 35-44 Female (Patient) Published: September 08

I wanted to add my experience(s) given most of these seem to fit my first experience, but not my second. The first time I had the endometrial biopsy I had 1 child already, but a C-section. I had taken 3 ibuprofen prior and the first part of the procedure (getting past the cervix) was awful. Many attempts, and I very well may have cried. Once doctor was past that point, the rest of the procedure was fine! Felt weird, but not painful. The second time around, last week, I was really freaked out ahead of time (and I read these stories on top of remembering my previous experience). I was not able to take ibuprofen, but took 2 Tylenol. Also, I had a second child a few years back, not a C-section. I think that made the difference. No problem with the cervix, and the other part of biopsy was fine again. So, I am not sure if it will ease some people's minds; it is possible for this to not hurt, or minimally be uncomfortable. Wish it could be that way for all.

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Comment from: JerryLynn, 35-44 Female (Patient) Published: September 07

I just had my first endometrial biopsy. I read all the stuff on here and was scared to death. Anyway, I took 3 Aleve and a tramadol 1 hour 15 minutes before my appointment time and it wasn't nearly as bad as I thought it would be. Procedure was, put gown on, spread legs, scooch down, regular speculum clamp, cough while she put in second cervix clamp; a few samples were suctioned and she removed both clamps and it was over. The cervical clamp was painful (I moaned and tensed up a bit) but it was doable. That was probably the worst part of it. The sample taking was easy (suctioning was it). So, it was about 2 to 3 minutes of pain, then it was over. A little sore. I relaxed for a couple of hours until the tramadol wore off. Then I was out food shopping with no problem. Moral of story, take pain killer prior to appointment.

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Comment from: Gina, 45-54 Female (Patient) Published: August 22

I had an endometrial biopsy yesterday. It was the most painful thing I have ever experienced. I have had a few colposcopies, and an HSG (hysterosalpingogram). Neither hurt as much. The pain was sudden and short lived but goodness! I did not expect how painful it would be. I have not had any children so insertion was very painful as was the collection. Ask if you can get something to numb the pain and I would suggest Advil or something an hour before.

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Comment from: Erin, 45-54 Female (Patient) Published: August 10

I had an endometrial biopsy today and took ibuprofen. The first 2 attempts using a pipette were slightly uncomfortable but very tolerable. Unfortunately they didn't get what they needed and had to clamp my cervix to try again. The clamp was excruciating when it was placed, I screamed as it went on. It continued to cause some pain for the rest of the procedure and was almost as painful when it was removed. They tried 3 more times with the pipette and only managed to get a tiny sample which may not be enough to test. The pipette itself caused more pain after clamp was placed and my quick procedure took about 30 minutes and may not get any results. I am 9 hours post procedure and having very little bleeding but have bad cramps and some pain in the area of my cervix. If your doctor can safely do the procedure without clamping the cervix, have them try that first as it was the clamp that caused the majority of my pain.

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Comment from: LaLaLinzi, 45-54 Female (Patient) Published: August 24

Endometrial biopsy was the most painful experience of my life. It is 24 hours later and I am not able to stand up straight without agonizing pain and cramps.

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