Encephalopathy Glossary of Terms
Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Alcohol abuse: Use of alcoholic beverages to excess, either on individual occasions ("binge drinking") or as a regular practice. For some individuals-children or pregnant women, for example-almost any amount of alcohol use may be legally considered "alcohol abuse," depending on local laws. Heavy alcohol abuse can cause physical damage and death.
Ammonia: A colorless gas with a very sharp odor. Made both by humans and by nature, ammonia dissolves easily in water and evaporates quickly. Liquid ammonia is found in many household cleaners. Ammonia is irritating to the skin, eyes, nose, throat, and lungs. Exposure to high concentrations in the air can severely burn the skin, eyes, throat, or lungs. In extreme cases, blindness, lung damage, or death can occur. Breathing lower concentrations causes coughing and nose and throat irritation. Swallowing ammonia may burn the mouth, throat, and stomach.
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Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
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Anoxia: 1. Strictly speaking, the absence of oxygen . 2. The near absence of oxygen. 3. Sometimes used loosely as a synonym for hypoxia .
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Anoxic: Pertaining to anoxia, an absence or near absence of oxygen.
Antihypertensive: Something that reduces high blood pressure (hypertension).
Apraxia: The inability to execute a voluntary motor movement despite being able to demonstrate normal muscle function. Apraxia is not related to a lack of understanding or to any kind of physical paralysis but is caused by a problem in the cortex of the brain.
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Ataxia: Wobbliness. Incoordination and unsteadiness due to the brain's failure to regulate the body's posture and regulate the strength and direction of limb movements. Ataxia is usually a consequence of disease in the brain, specifically in the cerebellum which lies beneath the back part of the cerebrum.
Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Blood count: The calculated number of white or red blood cells (WBCs or RBCs) in a cubic millimeter of blood.
Blood glucose: The main sugar that the body makes from the food in the diet. Glucose is carried through the bloodstream to provide energy to all cells in the body. Cells cannot use glucose without the help of insulin .
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".
Bovine: Having to do with cows and cattle, as in bovine spongiform encephalopathy (mad cow disease), bovine tuberculosis, and bovine growth hormone.
Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Brain swelling: See: Cerebral edema.
CBC: A commonly used abbreviation in medicine that stands for complete blood count , a set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Cirrhosis: An abnormal liver condition characterized by irreversible scarring of the liver. Alcohol and viral hepatitis B and C are among the many causes of cirrhosis. Cirrhosis can cause yellowing of the skin (jaundice), itching, and fatigue. Diagnosis of cirrhosis can be suggested by physical examination and blood tests, and can be confirmed by liver biopsy in some patients. Complications of cirrhosis include mental confusion, coma, fluid accumulation (ascites), internal bleeding, and kidney failure. Treatment of cirrhosis is designed to limit any further damage to the liver as well as complications. Liver transplantation is becoming an important option for patients with advanced cirrhosis.
Cocaine: The most potent stimulant of natural origin, a bitter addictive anesthetic (pain blocker) which is extracted from the leaves of the coca scrub (Erythroxylon coca) indigenous to the Andean highlands of South America.
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Coma: A state of deep unarousable unconsciousness.
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Complete blood count : A set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Congenital: Present at birth. A condition that is congenital is one that is present at birth. There are numerous uses of "congenital" in medicine. There are, for example, congenital abnormalities. (For more examples, see below.)
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Creatinine: A chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine.
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Delirium: A sudden state of severe confusion and rapid changes in brain function, sometimes associated with hallucinations and hyperactivity , in which the patient is inaccessible to normal contact. Symptoms may include inability to concentrate and disorganized thinking evidenced by rambling, irrelevant, or incoherent speech. There may be a reduced level of consciousness, sensory misperceptions and illusions, disturbances of sleep, drowsiness, disorientation to time, place, or person, and problems with memory.
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Dementia : Significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning.
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Dialysis: The process of cleansing the blood by passing it through a special machine. Dialysis is necessary when the kidneys are not able to filter the blood. Dialysis allows patients with kidney failure a chance to live productive lives. There are two types of dialysis: hemodialysis and peritoneal dialysis. Each type of dialysis has advantages and disadvantages. Patients can often choose the type of long term dialysis that best matches their needs.
Doppler ultrasound: A form of ultrasound that can detect and measure blood flow. Doppler ultrasound depends on the Doppler effect, a change in the frequency of a wave resulting here from the motion of a reflector, the red blood cell .
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EEG: Electroencephalogram, e technique for studying the electrical current within the brain. Electrodes are attached to the scalp. Wires attach these electrodes to a machine which records the electrical impulses. The results are either printed out or displayed on a computer screen. Electroencephalogram is abbreviated EEG.
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Encephalopathy: Disease, damage, or malfunction of the brain. In general, encephalopathy is manifested by an altered mental state that is sometimes accompanied by physical changes. Although numerous causes of encephalopathy are known, the majority of cases arise from infection, liver damage, anoxia, or kidney failure. The term encephalopathy is very broad and, in most cases, is preceded by various terms that describe the reason, cause, or special conditions of the patient that leads to brain malfunction. For example, anoxic encephalopathy means brain damage due to lack of oxygen, and hepatic encephalopathy means brain malfunction due to liver disease. Depending upon the cause and severity of the condition, symptoms may range from mild alterations in mental status to severe and potentially fatal manifestations such as dementia, seizures, and coma.
Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions , converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Floppy baby syndrome: A general medical reference to an abnormal condition of newborns and infants manifested by inadequate tone of the muscles. It can be due to a multitude of different neurologic and muscle problems. See also Hypotonia.
Glucose: The simple sugar (monosaccharide) that serves as the chief source of energy in the body. Glucose is the principal sugar the body makes. The body makes glucose from proteins, fats and, in largest part, carbohydrates. Glucose is carried to each cell through the bloodstream. Cells, however, cannot use glucose without the help of insulin . Glucose is also known as dextrose.
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Hepatic: Having to do with the liver. Pronounced hi-'pa-tik. From the Latin hepaticus derived from the Greek hepar meaning (not too surprisingly) the liver.
Hepatic encephalopathy : Brain dysfunction directly due to liver dysfunction, most often recognized in advanced liver disease. Hepatic encephalopathy may cause disturbances of consciousness and progress to coma .
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Hepatitis: Inflammation of the liver from any cause.
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Herniation: Abnormal protrusion of tissue through an opening. For example, a intervertebral disk (one situated between the vertebral bodies) can protrude and impinge on a nerve root.
Hyperglycemia: A high blood sugar. An elevated level specifically of the sugar glucose in the blood.
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Hypertensive: Having abnormally high blood pressure (hypertension). See also: Hypotensive; Normotensive.
Hypo-: Prefix meaning "low, under, beneath, down, below normal" as in hypocalcemia (low calcium in the blood), hypoglycemia (low blood sugar) and hyposensitivity. The opposite of hypo- is hyper- .
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Hypoglycemia : Low blood sugar (glucose). When symptoms of hypoglycemia occur together with a documented blood glucose under 45 mg/dl, and the symptoms promptly resolve with the administration of glucose, the diagnosis of hypoglycemia can be made with some certainty. Hypoglycemia is only significant when it is associated with symptoms.
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Hypoglycemic: Relating to hypoglycemia , an abnormally low level of the sugar glucose in the blood, usually a complication of diabetes, in which the body does not produce enough insulin to fully metabolize glucose.
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Hypotensive: Having abnormally low blood pressure (hypotension). See also: Hypertensive; Normotensive.
Hypotonia: Decreased tone of skeletal muscles. In a word, floppiness. Hypotonia is a common finding in cerebral palsy and other neuromuscular disorders. Untreated hypotonia can lead to hip dislocation and other problems. Treatment is via physical therapy. In some cases braces may be needed to permit a full range of movement despite hypotonia.
Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Insulin: A natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin.
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Involuntary: Done other than in accordance with the conscious will of the individual. The opposite of voluntary.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.
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Kidney transplant: Replacement of a diseased, damaged, or missing kidney with a donor kidney. Also called a renal transplant.
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Lethargy: 1. Abnormal drowsiness, stupor. 2. A state of indifference.
From the Greek lethargia, drowsiness.
Limb: The arm or leg.
Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.
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Liver disease: Liver disease refers to any disorder of the liver. The liver is a large organ in the upper right abdomen that aids in digestion and removes waste products from the blood.
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Low blood pressure : Any blood pressure that is below the normal expected for an individual in a given environment. Low blood pressure is also referred to as hypotension.
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Memory: 1. The ability to recover information about past events or knowledge. 2. The process of recovering information about past events or knowledge. 3. Cognitive reconstruction. The brain engages in a remarkable reshuffling process in an attempt to extract what is general and what is particular about each passing moment.
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Metabolic: Relating to metabolism, the whole range of biochemical processes that occur within us (or any living organism). Metabolism consists of anabolism (the buildup of substances) and catabolism (the breakdown of substances).
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MRI: Abbreviation and nickname for magnetic resonance imaging. For more information, see: Magnetic Resonance Imaging; Paul C. Lauterbur; Peter Mansfield.
Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Myoclonus: A condition of abnormal contraction of muscles or portions of muscles.
Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
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Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
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Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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Pediatric: Pertaining to children.
Physiologic: Something that is normal, neither due to anything pathologic nor significant in terms of causing illness.
Prognosis: 1. The expected course of a disease .
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good.
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Rehabilitation: The process of restoration of skills by a person who has had an illness or injury so as to regain maximum self-sufficiency and function in a normal or as near normal manner as possible. For example, rehabilitation after a stroke may help the patient walk again and speak clearly again.
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Shigella: A group of bacteria that normally inhabit the intestinal tract and cause infantile gastroenteritis, summer diarrhea of childhood and various forms of dysentery including epidemic and opportunistic bacillary dysentery. Named for the Japanese bacteriologist Kiyoshi Shiga (1870-1957).
Spongiform: Resembling a sponge in being soft and full of cavities, as in as in transmissible spongiform encephalopathy.
Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Therapy: The treatment of disease .
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Toxicity: The degree to which a substance can harm humans or animals.
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Toxin: One of a number of poisons produced by certain plants, animals, and bacteria.
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Transplant: The grafting of a tissue from one place to another, just as in botany a bud from one plant might be grafted onto the stem of another. The transplanting of tissue can be from one part of the patient to another (autologous transplantation), as in the case of a skin graft using the patient's own skin; or from one patient to another (allogenic transplantation), as in the case of transplanting a donor kidney into a recipient.
Trauma: Any injury , whether physically or emotionally inflicted. "Trauma" has both a medical and a psychiatric definition. Medically, "trauma" refers to a serious or critical bodily injury, wound, or shock . This definition is often associated with trauma medicine practiced in emergency rooms and represents a popular view of the term. In psychiatry , "trauma" has assumed a different meaning and refers to an experience that is emotionally painful, distressful, or shocking, which often results in lasting mental and physical effects.
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Twitching: Involuntary contractions of groups of muscle fibers. Also known as fasciculations. Fasciculations can occur in normal individuals without an associated disease or condition and can also occur as a result of illness, such as muscle cramps, nerve diseases, and metabolism imbalances.
Ultrasound: High-frequency sound waves. Ultrasound waves can be bounced off of tissues using special devices. The echoes are then converted into a picture called a sonogram. Ultrasound imaging, referred to as ultrasonography, allows physicians and patients to get an inside view of soft tissues and body cavities, without using invasive techniques. Ultrasound is often used to examine a fetus during pregnancy. There is no convincing evidence for any danger from ultrasound during pregnancy.
Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.
- Liver Blood Tests - Learn about liver blood tests used to detect liver damage disease such as fatty liver, cirrhosis, hepatitis, Tylenol liver damage, and more. This includes measuring the aminotransferases enzymes (AST and ALT levels)
- Low Blood Pressure - Learn about low blood pressure (hypotension). Low blood pressure is blood pressure below normal and symptoms may include: lightheadedness, dizziness, fainting upon standing (orthostatic hypotension). There are many causes of low blood pressure, and treatment is dependant upon the cause.
- Creatinine Blood Test - Learn more about the creatinine blood test, a test that measures kidney function. Abnormal creatinine levels in the blood may indicate kidney disease.
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