USES: Enalaprilat is an injectable form of the oral drug, enalapril. It is used to treat high blood pressure and heart failure when patients cannot take the oral form of this medication. Enalaprilat works by blocking an enzyme in the body called angiotensin-converting enzyme (ACE). This enzyme produces a chemical that narrows blood vessels and raises blood pressure.

OTHER USES: This drug may also be used to help prevent kidney problems in diabetics.

HOW TO USE: Inject this medication directly into a vein (IV) over 5 minutes or give IV over at least 5 minutes mixed in a dextrose- containing (e.g., D5W) or saline solution (NS) usually every 6 hours; or as directed by your doctor. The dosage is based on your medical condition and response to therapy. For details regarding mixing instructions, consult a pharmacist. You may be switched to an oral form of this drug when you are able to take medication by mouth. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Headache, dizziness, nausea, diarrhea, dry cough, or rash may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, irregular heartbeat, mental/mood changes, tingling of the hands/feet, vision problems (e.g., blurred vision or eye discomfort). Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fever, joint or muscle pain. This drug may rarely cause serious (possibly fatal) liver problems. If you notice any of the following highly unlikely but very serious side effects, seek immediate medical attention: yellowing of the eyes or skin, dark urine, stomach/abdominal pain, persistent fatigue, persistent nausea. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: itching, swelling (especially of the face, lips, tongue, or throat), severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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