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- What is enalapril, and how does it work (mechanism of action)?
- What brand names are available for enalapril?
- Is enalapril available as a generic drug?
- Do I need a prescription for enalapril?
- What are the side effects of enalapril?
- What is the dosage for enalapril?
- Which drugs or supplements interact with enalapril?
- Is enalapril safe to take if I'm pregnant or breastfeeding?
- What else should I know about enalapril?
What is enalapril, and how does it work (mechanism of action)?
Enalapril is a drug that is used for treating high blood pressure. It is in a class of drugs called angiotensin converting enzyme (ACE) inhibitors. ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II causes the arteries in the body to narrow, thereby elevating blood pressure. ACE inhibitors, such as enalapril, lower blood pressure by preventing the formation of angiotensin II thereby relaxing the arteries. ACE inhibitors also improve the effectiveness of the heart in patients with heart failure by reducing the blood pressure that the heart must maintain. Enalapril was approved by the FDA in December 1985.
What brand names are available for enalapril?
Is enalapril available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for enalapril?
What are the side effects of enalapril?
Enalapril is generally well tolerated, and side effects usually are mild and transient. A dry, persistent cough has been reported commonly with the use of ACE inhibitors. Coughing resolves after discontinuing the medication.
Other important side effects include:
- abdominal pain,
- loss of appetite,
- nausea and vomiting,
- chest pain,
- numbness or tingling in the hands or feet,
- rash, and a
- sore or swollen throat.
In rare instances, liver dysfunction and skin yellowing (jaundice) have been reported with ACE inhibitors. In susceptible individuals ACE inhibitors may reduce kidney function. Enalapril may cause hypersensitivity (allergic) reactions and angioedema (swelling of face, lips, tongue, throat).
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