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enalapril-felodipine extended release-oral (cont.)

PRECAUTIONS: Before using this product, tell your doctor your medical history, including: allergies (especially drug allergies), kidney problems, liver disease, heart or blood vessel problems, diabetes. Limit alcohol intake, as it may enhance certain side effects of this product. Also, avoid excessive sweating (such as very hot weather or heavy exercise) unless you drink enough extra fluids. Since this product may cause dizziness or fatigue, use caution if operating machinery or performing hazardous tasks. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. This product should be used only when clearly needed during the first 3 months of pregnancy. This product is not recommended for use during the last 6 months of pregnancy. Consult your doctor before using this drug. The enalapril in this product is excreted into breast milk. It is not known whether the felodipine is excreted into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Caution is advised when this product is used in the elderly.

DRUG INTERACTIONS: Tell your doctor of all nonprescription and prescription medication you may use, especially of: "water pills" (diuretics such as spironolactone, amiloride or triamterene), potassium supplements, azole antifungals (e.g., itraconazole, ketoconazole), other blood pressure medications (e.g., metoprolol, methyldopa, prazosin), intravenous (IV) calcium, certain psychiatric medications (e.g., lithium), certain anti-seizure drugs (e.g., phenytoin, carbamazepine, phenobarbital), cimetidine, trimethoprim-containing medications (e.g., sulfamethoxazole/trimethoprim), aspirin-like pain medications (e.g., ibuprofen), drugs for sleep (e.g., triazolam), macrolide antibiotics (e.g., clarithromycin, erythromycin), sedatives, tranquilizers, drugs for anxiety (e.g., diazepam), narcotic pain relievers (e.g., codeine), certain antihistamines (e.g., diphenhydramine). Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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