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February 10, 2010
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Emphysema

Medical Author: Benjamin Wedro, MD, FAAEM
Medical Editors: George Schiffman, MD, FCCP and Melissa Conrad Stöppler, MD

Viewer Comments

Featured emphysema patient discussions on experience with disease

"I was told in I I was told in I had COPD Emphysema; I was a heavy smoker, Fire fighter, mechanic and a rough life style. I smoked 4 packs a day. When I was in the hospital, I would leave my room in a wheelchair and go outside to smoke. Doctors get mad when you do that! After a near death episode, my pulmonary doctor told me about Chantix. After a couple of months I quit smoking and have no desire to. So check into it! My hardest adjustment is not being able to do minor things without I want to enjoy life with my children, wife and grand kids!"

"I was diagnosed with emphysema two years ago, and like a fool, I continued to smoke as the symptoms were not too bad then. Now, sadly, I’m faced with lung cancer, and my breathing has deteriorated. If only I had paid attention, I might not be where I am today. "

"How dumb could I have been? I watched my father die from emphysema, had a brother die from cancer related to smoking (only four years older than me), and yet for eight more years, I smoked and smoked, saying that it would never happen to me. I quit smoking a month ago and a week after I quit, I woke up with blood all over me and was coughing it up. I went to my doctor for help. After lots of tests and X-rays, I found out I have emphysema. Do I blame the cigarette companies? No, it was my own fault since the warnings were there and all my doctors told me to quit. I figured that it would never happen to me. I am proud of the fact that I was able to quit."


Top Searched Emphysema Terms:

stages, symptoms, subcutaneous, surgery, pulmonary interstitial, prognosis, acupuncture, causes, smoking
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Introduction to emphysema

The lungs are a pair of organs in the chest that are primarily responsible for the exchange of oxygen and carbon dioxide between the air we breathe and the blood.

The lung is composed of clusters of small air sacs (alveoli) divided by thin, elastic walls or membranes. Capillaries, the tiniest of blood vessels, run within these walls between the alveoli and allow blood and air to come near each other. The distance between the air in the lungs and the blood in the capillaries is very small, and allows molecules of oxygen and carbon dioxide to transfer across the membranes.

Air reaches the alveoli via the bronchial tree. The trachea splits into the right and left mainstem bronchi, which branch further into bronchioles and finally ends in the alveolar air sacs.

When we breathe in, air enters the lung and the alveoli expand. Oxygen is transferred onto hemoglobin molecules in the red blood cells to be transported to the rest of the body for use. As oxygen attaches to the red blood cell, carbon dioxide, the waste product of metabolism, detaches and crosses into the alveoli to be exhaled. When we breathe out, the alveoli get squeezed by the elasticity in their walls and air is pushed out of the lungs.

Picture of the Lungs and Pulmonary System

What is emphysema?

Emphysema is a long-term, progressive disease of the lung(s) and occurs when the alveolar walls are destroyed along with the capillary blood vessels that run within them. This lessens the total area within the lung where blood and air can come together, limiting the potential for oxygen and carbon dioxide transfer.

In early emphysema, there is associated inflammation of the small airways or bronchioles that limits the amount of air that can flow to the alveoli. In more severe emphysema, there is also loss of elasticity in the alveolar walls that have not been destroyed. When the patient breathes out, the alveoli and small airways collapse. This makes it hard for air to get out of the lungs and makes it even harder for new air to enter.

As more of the lung is destroyed and the lung cannot maintain oxygen concentrations in the bloodstream, the body compensates by gradually increasing the breathing rate. After a while, even hyperventilation (hyper=more + ventilation=breathing) cannot maintain adequate oxygen levels, and the arteries in the lung begin to constrict or narrow. The heart has to work harder to push blood into these narrower blood vessels, causing the blood pressure in the lung arteries to increase (pulmonary hypertension). Over time, the extra work requirement causes the heart muscle to enlarge (hypertrophy) and can cause heart failure.



Next: What are the causes or risk factors for emphysema? »

Emphysema - Describe Your Experience

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Emphysema

What are pulmonary arteries?

The human body has two major sets of blood vessels that distribute blood from the heart to the body. One set pumps blood from the right heart to the lungs and the other from the left heart to the rest of the body.

  • The portion of the circulation that distributes oxygen-rich blood from the left side of the heart, throughout the body, is referred to as the systemic circulation.
  • The blood then returns from the body to the right side of the heart and passes through the lungs to replenish oxygen.
  • It then returns to the left side of the heart for another round through the systemic circulation.
  • The portion of the circulation that distributes the blood from the right side of the heart to the lungs is referred to as the pulmonary (lung) circulation.
  • The pulmonary arteries are the major blood vessels that carry blood from the rig...

Read the Pulmonary Hypertension article »











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