Emphysema

Bronchitis Slideshow Asthma Myths Quiz Slideshow

Medical Author: Benjamin Wedro, MD, FAAEM
Medical Editors: George Schiffman, MD, FCCP and Melissa Conrad Stöppler, MD

• Introduction to emphysema
• What is emphysema?
• What are the causes or risk factors for emphysema?
• What are symptoms of emphysema?
• How is emphysema diagnosed?
• Physical examination
• Exams and tests
• What is the treatment for emphysema?
• Smoking cessation
• Medications
• Pulmonary rehabilitation
• Surgery
• Emphysema At A Glance
• Patient Discussions: Emphysema - Describe Your Experience

Featured emphysema patient discussions on experience with disease "I was told in I I was told in I had COPD Emphysema; I was a heavy smoker, Fire fighter, mechanic and a rough life style. I smoked 4 packs a day. When I was in the hospital, I would leave my room in a wheelchair and go outside to smoke. Doctors get mad when you do that! After a near death episode, my pulmonary doctor told me about Chantix. After a couple of months I quit smoking and have no desire to. So check into it! My hardest adjustment is not being able to do minor things without I want to enjoy life with my children, wife and grand kids!" "I was diagnosed with emphysema two years ago, and like a fool, I continued to smoke as the symptoms were not too bad then. Now, sadly, I’m faced with lung cancer, and my breathing has deteriorated. If only I had paid attention, I might not be where I am today. " "How dumb could I have been? I watched my father die from emphysema, had a brother die from cancer related to smoking (only four years older than me), and yet for eight more years, I smoked and smoked, saying that it would never happen to me. I quit smoking a month ago and a week after I quit, I woke up with blood all over me and was coughing it up. I went to my doctor for help. After lots of tests and X-rays, I found out I have emphysema. Do I blame the cigarette companies? No, it was my own fault since the warnings were there and all my doctors told me to quit. I figured that it would never happen to me. I am proud of the fact that I was able to quit." Read All Comments on Emphysema » Top Searched Emphysema Terms: stages, symptoms, subcutaneous, surgery, pulmonary interstitial, prognosis, acupuncture, causes, smoking Patient Discussions are not a substitute for professional medical advice, or treatment. See the disclaimer at the bottom of the comments page.

Introduction to emphysema

The lungs are a pair of organs in the chest that are primarily responsible for the exchange of oxygen and carbon dioxide between the air we breathe and the blood.

The lung is composed of clusters of small air sacs (alveoli) divided by thin, elastic walls or membranes. Capillaries, the tiniest of blood vessels, run within these walls between the alveoli and allow blood and air to come near each other. The distance between the air in the lungs and the blood in the capillaries is very small, and allows molecules of oxygen and carbon dioxide to transfer across the membranes.

Air reaches the alveoli via the bronchial tree. The trachea splits into the right and left mainstem bronchi, which branch further into bronchioles and finally ends in the alveolar air sacs.

When we breathe in, air enters the lung and the alveoli expand. Oxygen is transferred onto hemoglobin molecules in the red blood cells to be transported to the rest of the body for use. As oxygen attaches to the red blood cell, carbon dioxide, the waste product of metabolism, detaches and crosses into the alveoli to be exhaled. When we breathe out, the alveoli get squeezed by the elasticity in their walls and air is pushed out of the lungs.

What is emphysema?

Emphysema is a long-term, progressive disease of the lung(s) and occurs when the alveolar walls are destroyed along with the capillary blood vessels that run within them. This lessens the total area within the lung where blood and air can come together, limiting the potential for oxygen and carbon dioxide transfer.

In early emphysema, there is associated inflammation of the small airways or bronchioles that limits the amount of air that can flow to the alveoli. In more severe emphysema, there is also loss of elasticity in the alveolar walls that have not been destroyed. When the patient breathes out, the alveoli and small airways collapse. This makes it hard for air to get out of the lungs and makes it even harder for new air to enter.

As more of the lung is destroyed and the lung cannot maintain oxygen concentrations in the bloodstream, the body compensates by gradually increasing the breathing rate. After a while, even hyperventilation (hyper=more + ventilation=breathing) cannot maintain adequate oxygen levels, and the arteries in the lung begin to constrict or narrow. The heart has to work harder to push blood into these narrower blood vessels, causing the blood pressure in the lung arteries to increase (pulmonary hypertension). Over time, the extra work requirement causes the heart muscle to enlarge (hypertrophy) and can cause heart failure.

Emphysema - Describe Your Experience

The MedicineNet physician editors ask:

Please describe your experience with emphysema.

Comment submissions for this question have ended.
See 26 Viewer Comments

View Comments

Suggested Reading by Our Doctors

• prednisone, Deltasone, Liquid Pred - Defines the medication prednisone (Deltasone, Liquid Pred) a drug used for suppressing the immune system and inflammation. Article includes descriptions, uses, drug interaction, and side effects.
• Hemoglobin - Read about hemoglobin - the protein molecule in red blood cells. Learn what normal, low, and high level hemoglobin counts mean on MedicineNet.com
• Pneumonia - Learn pneumonia symptoms, causes, treatment, signs, diagnosis and types: viral and bacterial (Pneumocystis carinii, Klebsiella, Mycoplasma, Chlamydia pneumoniae).

Read more Emphysema related articles »

Latest Medical News

• Repairing Injured Lungs May Boost Organ Donations
• Bacteria May Lurk on Your Showerhead
• Swine Flu: Who's Most at Risk?
• Early COPD Treatment Slows Disease