eflornithine, Vaniqa (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
DOSING: Eflornithine should be applied in a thin layer around the affected facial areas and chin and rubbed-in thoroughly. It is applied twice daily with at least eight hours between applications or as directed by a physician. Eflornithine should not be washed away from the skin for at least eight hours after application. Cosmetics and sunscreens may be applied once the treated area has dried. Hair removal techniques such as tweezing should be continued. The hands should be washed immediately after using eflornithine.
DRUG INTERACTIONS: No studies have been done to determine if eflornithine interacts with other drugs applied to the skin.
PREGNANCY: There have been no studies of eflornithine therapy in pregnant women.
NURSING MOTHERS: It is not known if eflornithine is secreted into breast milk.
SIDE EFFECTS: The most common side effects seen with eflornithine are acne, swollen patches that are sometimes reddened and contain a buried hair (pseudofolliculitis barbae), headache, skin itching, stinging, burning, dry or tingling skin, rash, hair loss, and ingrown hairs. Less common side effects are bleeding skin, swollen lips, nausea, numbness, contact dermatitis, and herpes simplex.
Reference: FDA Prescribing Information
Last Editorial Review: 3/7/2013
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