GENERIC NAME: efinaconazole
BRAND NAME: Jublia
DRUG CLASS AND MECHANISM: Efinaconazole is a topical (applied to the skin) antifungal used for the local treatment of fungal infections of the toenails. Efinaconazole destroys fungal cells by inhibiting fungal lanosterol 14α-demethylase, an enzyme required to make ergosterol, an important fungal cell wall component. Without cell walls fungus cannot survive. Efinaconazole was approved by the FDA in June, 2014.
PRESCRIBED FOR: Efinaconazole is a prescription medicine used to treat fungal infections of the toenails. It is FDA approved for the treatment of onychomycosis of the toenails due to Trichophyton rubrum and Trichophyton mentagrophytes.
SIDE EFFECTS: The most common side effects of treatment are mainly irritation of the area(s) efinaconazole is applied to. Side effects include:
GENERIC AVAILABLE: No
PREPARATIONS: Topical solution: 10%
STORAGE: Efinaconazole should be stored at room temperature, from 15 C to 30 C (59 C to 86 F). Efinaconazole is flammable and should be protected from heat or flames. Efinaconazole containers should be stored in an upright position. Keep efinaconazole and all medications out of the reach of children.
DOSING: Efinaconazole is applied to the affected toenail(s) once daily for 48 weeks. When applying efinaconazole, patients should make sure that the toenails, toenail beds, and surrounding skin are completely covered. For best results, apply efinaconazole to dry toenails. Patients should wait for at least 10 minutes after showering, bathing, or washing before applying efinaconazole. Patients should avoid pedicures, use of nail polish, or cosmetic nail products while using efinaconazole. Efinaconazole is only intended for use on toenails and surrounding skin.
Quick GuideNail Color and Texture: What Nails Say About Your Health
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.