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November 25, 2009
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Medications and Drugs

GENERIC NAME: EFAVIRENZ - ORAL (eh-FAV-er-enz)

BRAND NAME(S): Sustiva

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: This medication is used to treat HIV infection in combination with other anti-HIV medications. If efavirenz is the only drug you take to treat HIV infection, it may stop working. Consult your doctor or pharmacist for more details.

HOW TO USE: Take this drug by mouth, generally once daily as directed. Take on an empty stomach with a glass of water. Taking efavirenz with food, especially a high-fat meal can lead to increased blood levels of the drug and increase your risk of having side effects. Best taken at bedtime during the first month of use. Using this drug regularly at bedtime may decrease certain side effects. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not take more or less of this drug than prescribed, or stop taking it unless directed to do so by your doctor. Read the patient information leaflet provided by your pharmacist.

SIDE EFFECTS: Dizziness, drowsiness or trouble sleeping may occur. If these effects persist or worsen, notify your doctor promptly. Report promptly: skin rash. Unlikely but report promptly: mood/mental changes (e.g., depression, and in rare cases, thoughts of suicide), dark urine, stomach pain, yellowing eyes or skin, fever. Very unlikely but report promptly: seizures. Some side effects (such as dizziness, drowsiness, certain mental changes) may decrease as your body adjusts to the drug. Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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