The following are health and medical definitions of terms that appear in the Eczema article. Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Allergen: A substance that is foreign to the body and can cause an allergic reaction in certain people. For examples, pollen, dander, mold.
Allergic contact dermatitis: A red, itchy, weepy reaction where the skin has come into contact with a substance that the immune system recognizes as foreign, such as poison ivy, poison oak or poison sumac or certain preservatives in creams and lotions. This type of reaction reflects a specific sensitivity or allergy to a specific substance. Also called allergic contact eczema.
Allergic contact eczema: Also called allergic contact dermatitis, this is a red, itchy, weepy reaction where the skin has come into contact with a substance that the immune system recognizes as foreign, such as poison ivy or certain preservatives in creams and lotions.
Allergy : A misguided reaction to foreign substances by the immune system , the body system of defense against foreign invaders, particularly pathogens (the agents of infection ). The allergic reaction is misguided in that these foreign substances are usually harmless. The substances that trigger allergy are called allergen. Examples include pollens , dust mite, molds , danders , and certain foods. People prone to allergies are said to be allergic or atopic .
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Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.
Arms: An appendage in anatomy and in clinical trials. See: Arm.
Asthma : A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs ( alveoli ) or the lung tissue (the parenchyma of the lung) itself.
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Atopic: Prone to allergies or characterized by allergy.
Atopic dermatitis : A skin disease characterized by areas of severe itching, redness, scaling, and loss of the surface of the skin (excoriation). When the eruption ( rash ) has been present for a prolonged time, chronic changes occur due to the constant scratching and rubbing known as lichenification (thickening of the skin with accentuation of the skin lines to form a crisscross pattern).
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
Burn: Damage to the skin or other body parts caused by extreme heat, flame, contact with heated objects, or chemicals. Burn depth is generally categorized as first, second, or third degree. The treatment of burns depends on the depth, area, and location of the burn, as well as additional factors, such as material that may be burned onto or into the skin. Treatment options range from simply applying a cold pack to emergency treatment to skin grafts.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Circulatory: Having to do with the circulation, the movement of fluid in a regular or circuitous course. Although the adjective "circulatory" need not necessarily refer to the circulation of the blood, for all practical purposes today it does. A circulatory problem is taken usually to be a problem with the blood circulation, for example with heart failure.
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Condition: The term "condition" has a number of biomedical meanings including the following: - An unhealthy state, such as in "this is a progressive condition."
- A state of fitness, such as "getting into condition."
- Something that is essential to the occurrence of something else; essentially a "precondition."
- As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.
Contact dermatitis: A skin condition caused by contact between skin and some substance. Includes irritant contact dermatitis (a rash brought on purely by repeated irritation from a substance such as water causing "dish pan hands") and allergic contact dermatitis (involving a specific sensitivity or allergy to a specific substance such as poison ivy).
Contact eczema: A localized reaction that includes redness, itching, and burning where the skin has come into contact with an allergen (an allergy-causing substance) or with an irritant such as an acid, a cleaning agent or another chemical.
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Corticosteroid: Any of the steroid hormones made by the cortex (outer layer) of the adrenal gland. Cortisol is a corticosteroid.
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Cream: A word with many meanings that, in medicine and pharmacy, refers to a water-soluble preparation applied to the skin. An ointment differs from a cream in that it has an oil base.
Dandruff: A mild skin condition that produces white flakes that may be shed and fall from the hair.
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Dermatitis: Inflammation of the skin, either due to direct contact with an irritating substance, or to an allergic reaction. Symptoms of dermatitis include redness, itching, and in some cases blistering.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Dyshidrotic eczema: Irritation of the skin on the palms of hands and soles of the feet characterized by clear, deep blisters that itch and burn.
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Eczema: A particular type of inflammatory reaction of the skin in which there are typically vesicles (tiny blister-like raised areas) in the first stage followed by erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin. Eczema characteristically causes itching and burning of the skin.
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Edema: The swelling of soft tissues as a result of excess water accumulation.
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Elidel: Brand name of pimecrolimus.
Environment: The sum of the total of the elements, factors and conditions in the surroundings which may have an impact on the development , action or survival of an organism or group of organisms.
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Exacerbate: To make worse. For example, smoking may exacerbate systemic lupus erythematosus.
Family: 1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.
Family history: The family structure and relationships within the family, including information about diseases in family members.
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FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Feet: The plural of foot, both an anatomic structure and a unit of measure.
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Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Hay fever: A seasonal allergy to airborne particles characterized by itchy eyes, runny nose, nasal congestion, sneezing, itchy throat, and excess mucus.
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Health: As officially defined by the World Health Organization, a state of complete physical, mental, and social well-being, not merely the absence of disease or infirmity.
Immune: Protected against infection. The Latin immunis means free, exempt.
Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunosuppressant: An agent that can suppress or prevent the immune response. Immunosuppressants are used to prevent rejection of a transplanted organ and to treat autoimmune diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease. Some treatments for cancer act as immunosuppressants. Also called an immunodepressant.
Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
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Neurodermatitis: Scaly patches of skin on the head, lower legs, wrists, or forearms caused by a localized itch such as from an insect bite that becomes intensely irritated when scratched.
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Nickel: A silver-white metallic element. Long-term exposure to nickel, such as from jewelry, can cause a form of contact dermatitis called nickel dermatitis. Exposure to nickel fumes can cause nasal cancer and lung cancer.
Nummular eczema: Coin-shaped patches of irritated skin-most common on the arms, back, buttocks, and lower legs that may be crusted, scaling , and extremely itchy.
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Phototherapy: Treatment with light. For example, a newborn with jaundice may be "put under the lights."
Pimecrolimus: A chemical used to treat atopic dermatitis (eczema). Pimecrolimus prevents the activation of T cells by blocking the effects of chemicals called cytokines that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation. Brand name: Elidel. For more information, see: Pimecrolimus.
Poison: Any substance that can cause severe distress or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in too large of a quantity. Poison treatment depends on the substance: if there are treatment instructions on the substance's container and you are sure it contained no other item, follow those directions immediately. Always contact your nearest Poison Control Center if you are concerned about possible poison ingestion.
Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.
Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.
Scaling: Abnormal shedding or accumulation of an upper layer of skin (the stratum corneum ).
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Seborrheic dermatitis: A medical name for what is popularly called seborrhea.
Seborrheic eczema: Yellowish, oily, scaly patches of skin on the scalp, face, and occasionally other parts of the body.
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Sedative: A drug that calms a patient down, easing agitation and permitting sleep. Sedatives generally work by modulating signals within the central nervous system. These sedatives can dangerously depress important signals needed to maintain heart and lung function if they are misused or accidentally combined, as in the case of combining prescription sedatives with alcohol. Most sedatives also have addictive potential. For these reasons, sedatives should be used under supervision, and only as needed.
Side effects: Problems that occur when treatment goes beyond the desired effect. Or problems that occur in addition to the desired therapeutic effect.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.
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Stasis: Stasis refers to a stoppage or slowdown in the flow of blood (or other body fluid such as lymph).
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Stasis dermatitis: A skin irritation on the lower legs generally related to circulatory problems.
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Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Substance: 1. Material with particular features, as a pressor substance.
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse.
Sweat: A colorless transparent acidic fluid with a distinctive odor secreted by the small tubular sudoriferous (sweat) glands situated within the skin and under it in the subcutaneous tissue . The sweat glands discharge their fluid through tiny openings in the surface of the skin.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
Tacrolimus: A drug that suppresses the immune system and prevents transplant rejection . The drug acts by inhibiting the activation of T cells .
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Therapy: The treatment of disease .
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Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.
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Trigger: Something that either sets off a disease in people who are genetically predisposed to developing the disease, or that causes a certain symptom to occur in a person who has a disease. For example, sunlight can trigger rashes in people with lupus.
Vesicular: Pertaining to the presence of one or more vesicles . A vesicle is a small blister .
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- hydroxyzine, Vistaril, Atarax - Specifies the medication hydroxyzine (Vistaril, Atarax), a drug used for the relief of nasal and non-nasal symptoms of various allergic conditions such as seasonal allergic rhinitis.
- Skin Biopsy - Read about the skin biopsy procedure and what to expect if your doctor orders this procedure for a lesion.
- Rash - Learn about rash causes, symptoms, diagnosis and treatment. Common skin rashes include poison ivy, hives, shingles, eczema, contact dermatitis, ringworm, psoriasis and impetigo.
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