Dysthymia (Persistent Depressive Disorder)

  • Medical Author:
    Roxanne Dryden-Edwards, MD

    Dr. Roxanne Dryden-Edwards is an adult, child, and adolescent psychiatrist. She is a former Chair of the Committee on Developmental Disabilities for the American Psychiatric Association, Assistant Professor of Psychiatry at Johns Hopkins Hospital in Baltimore, Maryland, and Medical Director of the National Center for Children and Families in Bethesda, Maryland.

  • Medical Editor: Melissa Conrad Stöppler, MD
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Understanding Depression Slideshow

Quick GuideMyths and Facts About Depression

Myths and Facts About Depression

Are there support groups for people with persistent depressive disorder?

DepNet.org

MDJunction.com

National Alliance for the Mentally Ill (NAMI)
2101 Wilson Boulevard Suite 302
Arlington, VA 22201
HelpLine: 800-950-NAMI [6264]

REFERENCES:

Alim, et al. "Trauma exposure, posttraumatic stress disorder and depression in an African-American primary care population." Journal of the National Medical Association 98.10 Oct. 2006: 1630-1636.

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Washington, D.C.: American Psychiatric Association, 2013.

Ballesteros, J. "Orphan comparisons and indirect meta-analysis: A case study on antidepressant efficacy in dysthymia comparing tricyclic antidepressants, selective serotonin reuptake inhibitors, and monoamine oxidase inhibitors by using general linear models." Journal of Clinical Psychopharmacology 25.2 (2005): 127–131.

Bhatia, S.K., and S.C. Bhatia. "Childhood and adolescent depression." American Family Physician 75.1 Jan. 2007: 73-80.

Bruder, G.E., J.W. Stewart, P.J. McGrath, et al. "Abnormal functional brain asymmetry in depression: evidence of biologic commonality between major depression and dysthymia." Psychiatry Research 196.2-3 Apr. 2012: 250-254.

Byers, A.L., K.E. Covinsky, K. Yaffe, et al. "Dysthymia and depression increase risk of dementia and mortality among older veterans." American Journal of Geriatric Psychiatry 20.8 Aug. 2012: 664-672.

Ciechanowski, P., et al. "Community-integrated, home-based depression treatment in older adults: a randomized controlled trial." Journal of the American Medical Association 291.13 Apr. 2004: 1569-1577.

Cuijpers, P., A. van Straten, J. Schuurmans, P. van Oppen, S.D. Hollon, and G. Andersson. "Psychotherapy for chronic major depression and dysthymia: a meta-analysis." Clinical Psychology Review 30.1 Feb. 2010: 51-62.

Gladstone, T.R.G., W.R. Beardslee, and E.E. O'Connor. "The prevention of adolescent depression." Psychiatric Clinics of North America 34.1 Mar. 2011: 35-52.

Hamidian, S., A. Omidi, S.M. Mousavinasab, and G. Naziri. "Comparison of the effect of mindfulness-based cognitive therapy accompanied by pharmacotherapy with pharmacotherapy alone in treating dysthymic patients." Iran Red Cres J 15.3 (2013).

Hellerstein, D.J., S.T. Batchelder, S.A. Little, M.J. Fedak, D. Kreditor, and J. Rosenthal. "Venlafaxine in the treatment of dysthymia: an open-label study." Clinical Psychiatry 60.12 Dec. 1999: 845-849.

Jimenez, D.E, M. Alegria, C. Chen, et al. "Prevalence of Psychiatric Illnesses among Ethnic Minority Elderly." Journal of American Geriatric Society 58.2 Feb. 2010: 256-264.

Koran, L.M., E.N. Aboujaoude, and N.N. Gamel. "Duloxetine treatment of dysthymia and double depression: an open-label trial." Journal of Clinical Psychiatry 68.5 May 2007: 761-765.

Lyoo, I.K., J.S. Kwon, S.J. Lee, M.H. Hann, C. Chang, Seo, S.I. Lee, and P.F. Renshaw. "Decrease in genu of the corpus callosum in medication-naïve, early-onset dysthymia and depressive personality disorder." Biological Psychiatry 52.12 (2002): 1134-1143.

Riolo, S.A., T.A. Nguyen, and C.A. King. "Prevalence of depression by race/ethnicity: Findings from the National Health and Nutrition Examination Survey III." Journal of Public Health 95.6 June 2005: 998-1000.

Sansone, R.A., and L.A. Sansone. "Dysthymic disorder: forlorn and overlooked?" Psychiatry (Edgmont) 6.5 May 2009: 46-51.

Sansone, R.A., and L.A. Sansone. "Early- versus late-onset dysthymia: A meaningful clinical distinction?" Psychiatry (Edgmont) 6.11 Nov. 2009: 14-17.

Sovern, M.A. "Treatment of dysthymic disorder in older adults." University of Toledo (2008).

Medically Reviewed by a Doctor on 4/8/2016
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