dutasteride (Avodart) (cont.)

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Medical and Pharmacy Editor:

Patients must contact their healthcare professional if unusual reactions to dutasteride occur.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Dutasteride is available as 0.5 mg liquid-filled capsules.

STORAGE: Dutasteride capsules should be stored between 15 C to 30 C (59 F to 86 F).

DOSING: The recommended dose of dutasteride is 0.5 mg once daily; do not chew the medication and do not administer to pediatric patients.

DRUG INTERACTIONS: Medications such as ketoconazole (Nizoral), cimetidine (Tagamet), diltiazem (Cardizem), verapamil (Calan), ritonavir (Norvir) and clarithromycin (Biaxin) slow down the breakdown of dutasteride. This may lead to increased levels of dutasteride in the body, increasing side effects such as decreased libido, erectile dysfunction, and impotence.

Medications such as carbamazepine (Tegretol) and primidone (Mysoline) increase the breakdown of dutasteride in the body. This may lead to decreased levels of dutasteride in the body, lowering the beneficial effects of the medication.

PREGNANCY: Dutasteride is not recommended to pregnant females because it can cause birth defects in the unborn child.

NURSING MOTHERS: It is not known whether dutasteride enters breast milk.

REFERENCE: FDA Prescribing Information.


Medically Reviewed by a Doctor on 12/22/2014


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