dutasteride (Avodart)

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GENERIC NAME: dutasteride

BRAND NAME: Avodart

DRUG CLASS AND MECHANISM: Dutasteride is a medication used for the treatment of benign prostatic hyperplasia (BPH) also known as an enlarged prostate. Dutasteride belongs to a class of medication called 5-alpa reductase inhibitors. Male hormone dihydrotestosterone (DHT) is primarily responsible for development and enlargement of the prostate gland. Testosterone is converted into DHT by 5-alpha reductase enzyme. Dutasteride blocks 5-alpha reductase enzyme and prevents excessive DHT production in the prostate gland. This delays the progression of an enlarged prostate and improves symptoms of BPH.

The FDA approved dutasteride in November 2001.

PRESCRIBED FOR: Dutasteride is used for the treatment of benign prostatic hyperplasia. It improves symptoms of enlarged prostate, reduces retaining of urine, and reduces the risk of the need for prostate surgery.

SIDE EFFECTS: Dutasteride causes many sexual side effects.

Common side effects are:

  • Impotence
  • Decreased libido
  • Ejaculation disorder
  • Breast enlargement and tenderness.

Allergic reaction such as swelling under the skin may occur.

Dutasteride also increases risk of high-grade prostate cancer.

Medically Reviewed by a Doctor on 12/22/2014



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