dutasteride (Avodart)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

What is the dosage for dutasteride-oral?

The recommended dose of dutasteride is 0.5 mg once daily; do not chew the medication and do not administer to pediatric patients.

Which drugs or supplements interact with dutasteride-oral?

Medications such as ketoconazole (Nizoral), cimetidine (Tagamet), diltiazem (Cardizem), verapamil (Calan), ritonavir (Norvir) and clarithromycin (Biaxin) slow down the breakdown of dutasteride. This may lead to increased levels of dutasteride in the body, increasing side effects such as decreased libido, erectile dysfunction, and impotence.

Medications such as carbamazepine (Tegretol) and primidone (Mysoline) increase the breakdown of dutasteride in the body. This may lead to decreased levels of dutasteride in the body, lowering the beneficial effects of the medication.

Is dutasteride-oral safe to take if I'm pregnant or breastfeeding?

Dutasteride is not recommended to pregnant females because it can cause birth defects in the unborn child.

It is not known whether dutasteride enters breast milk.

What else should I know about dutasteride-oral?

What preparations of dutasteride-oral are available?

Dutasteride is available as 0.5 mg liquid-filled capsules.

How should I keep dutasteride-oral stored?

Dutasteride capsules should be stored between 15 C to 30 C (59 F to 86 F).

REFERENCE: FDA Prescribing Information.

Last Editorial Review: 10/25/2016

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Reviewed on 10/25/2016
References
REFERENCE: FDA Prescribing Information.

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