Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Biliary: Having to do with the gallbladder , bile ducts , or bile. The biliary system itself consists of the gallbladder and bile ducts and, of course, the bile.
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Cholecystitis: Inflammation of the gallbladder, a complication of gallstones which are formed by cholesterol and pigment (bilirubin) in bile. (Bile is produced in the liver and stored in the gallbladder). Cholecystitis is frequently associated with infection in the gallbladder. Risk factors for cholesterol gallstones include age, obesity, female gender, multiple pregnancies, birth control pills, and heredity. The most common symptom is pain in the upper abdomen. Diagnosis is usually made with ultrasound of the abdomen. Some patients have no symptoms. Patients with mild and infrequent symptoms may consider oral medication to dissolve gallstones. Surgery (standard or laparoscopic) is considered for patients with severe symptoms and for patient with cholecystitis.
Cholecystokinin: Abbreviated CCK. A polypeptide hormone that stimulates the contraction of the gallbladder with release of bile and the secretion of pancreatic enzymes into the small intestine. CCK is secreted by cells lining the upper intestine and by the hypothalamus. Hypothalamic cholecystokinin is a neurotransmitter. Called also pancreozymin.
Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Colic: An attack of crying and apparent abdominal pain in early infancy. This is a common condition, occurring in about 1 in every 10 babies. Colic is characterized by episodes of irritability, loud crying, and what appears to be abdominal pain with the legs drawn up and the abdomen feeling rigid.
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Duct: A passage or a tube with well-defined walls suitable for the conveyance of air or liquids, as the bile duct and the pancreatic duct.
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Duodenal: Pertaining to the duodenum, part of the small intestine. As in duodenal ulcer or duodenal biliary drainage.
Duodenal biliary drainage: A procedure used to diagnose gallstones when suspicion is high but other tests are negative. A thin tube is passed through a nostril down the throat, through the esophagus and stomach, into the duodenum. Once the tube is in place, a synthetic hormone related to cholecystokinin is injected IV. It causes the gallbladder to contract and squeeze out bile into the duodenum. The bile then is sucked up through the tube and examined for the presence of cholesterol and pigment particles under a microscope. A modification of duodenal biliary drainage involves collection of bile through an endoscope at the time of EGD (esophagogastroduodenoscopy) or ERCP (endoscopic retrograde cholangio-pancreatography).
Duodenum: The first part of the small intestine. The duodenum extends from the pylorus at the bottom of the stomach to the jejunum, the second part of the small intestine. The duodenum is a common site for the formation of peptic ulcers. We often live with words without thinking where they come from or what they originally meant. That is the case for me with the duodenum. For decades, this writer knew the duodenum as a short but troubled sector of the small intestine. Only today did I learn that the duodenum began as the dodeka-daktulon, twelve fingers to the Greeks, who astutely observed that the duodenum is about 12 finger-breadths long. In German, the popular term for duodenum is Zwölffingerdarm, the 12-finger intestine.
EGD: Esophagogastroduodenoscopy.
Endoscope: A lighted optical instrument used to get a deep look inside the body and examine organs such as the throat or esophagus. An endoscope can be rigid or flexible.
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Endoscopy: Endoscopy is a broad term used to described examining the inside of the body using an lighted, flexible instrument called an endoscope. In general, an endoscope is introduced into the body through a natural opening like the mouth or anus. Although endoscopy can include examination of other organs, the most common endoscopic procedures evaluate the esophagus (swallowing tube), stomach, and portions of the intestine.
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ERCP: Endoscopic retrograde cholangiopancreatography.
Esophagogastroduodenoscopy : Also known as EGD or upper endoscopy. A procedure that enables the examiner (usually a gastroenterologist) to examine the esophagus (the swallowing tube), stomach, and duodenum (the first portion of small bowel) using a thin flexible tube (a "scope") that can be looked through or seen on a TV monitor. (A great crossword puzzle/trivia term!)
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Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.
Fluoroscopy: An x-ray procedure that makes it possible to see internal organs in motion.
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Gallbladder: A pear-shaped organ just below the liver that stores the bile secreted by the liver. During a fatty meal, the gallbladder contracts, delivering the bile through the bile ducts into the intestines to help with digestion. Abnormal composition of bile leads to formation of gallstones, a process termed cholelithiasis. The gallstones cause cholecystitis, inflammation of the gallbladder.
Gallstones : Stones that form when substances in the bile harden. Gallstones can be as small as a grain of sand or as large as a golf ball. There can be just one large stone, hundreds of tiny stones, or any combination.
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Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.
Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
Microscopic: So small it cannot be seen without the aid of microscope. As opposed to macroscopic (large enough to be seen with naked eye). A tiny tumor is microscopic while a big tumor is macroscopic.
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Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
Nostril: One of the openings in the nose that allows air to flow in and out of the nasal cavities. The word nostril comes from the Old English nosu, nose + thyrel, hole = the nose hole.
Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.
Pancreatic: Having to do with the pancreas, a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.
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Pancreatitis : Inflammation of the pancreas. Of the many diverse causes of pancreatitis , the most common are alcohol and gallstones .
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Pigment: A substance that gives color to tissue. Pigments are responsible for the color of skin, eyes, and hair.
Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.
Spasm: A brief, automatic jerking movement. A muscle spasm can be quite painful, with the muscle clenching tightly. A spasm of the coronary artery can cause angina. Spasms in various types of tissue may be caused by stress, medication, over-exercise, or other factors.
Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus .
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