Medications and Drugs
GENERIC NAME: DULOXETINE - ORAL (dull-OX-eh-teen)
BRAND NAME(S): Cymbalta
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
USES: Duloxetine is used to treat major depression and also used to relieve nerve pain (peripheral neuropathy) in diabetics. This medication works by restoring the balance of two kinds of natural substances (neurotransmitters known as serotonin and norepinephrine) in the brain, thereby improving mood and feelings of well-being.
HOW TO USE: Take this medication by mouth; with or without food usually once or twice a day depending on the amount that you take; or as directed by your doctor. This medicine should not be crushed, chewed or mixed with food or liquid. Swallow it whole. Dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. It is important to continue taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. It may take between 1 to 4 weeks before the full benefit of this drug takes effect. Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: Nausea, dry mouth, constipation, loss of appetite, fatigue, drowsiness, dizziness, increased sweating, blurred vision, rash, or itching may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual or severe mental/mood changes (e.g., anxiety, mania), weight loss, change in sexual desire and ability, uncontrolled movements (tremor), difficulty urinating. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: chest pain, stomach pain, black stools, vomit that looks like coffee grounds, easy bruising/bleeding, unusual bleeding, seizures. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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