- Take the Liver Disease Quiz
- A Visual Guide to Hepatitis Slideshow
- Take the Alcohol Quiz
- Patient Comments: Drug-Induced Liver Disease - Describe Your Experience
- Patient Comments: Drug-Induced Liver Disease - Causes
- Patient Comments: Drug-Induced Liver Disease - Hepatitis
- Patient Comments: Drug-Induced Liver Disease - Treatment
- Find a local Gastroenterologist in your town
- What is drug-induced liver disease?
- What is the liver?
- What are the symptoms of liver disease?
- How do drugs cause liver disease?
- What types of liver disease do drugs cause?
- Elevated blood levels of liver enzymes
- Acute and chronic hepatitis
- Acute liver failure
- Steatosis (fatty liver)
- Hepatic vein thrombosis
- How is drug-induced liver disease diagnosed?
- What is the treatment for drug-induced liver disease?
- What are some important examples of drug-induced liver disease?
What are the symptoms of liver disease?
Patients with mild liver disease may have few or no symptoms or signs. Patients with more serious disease develop symptoms and signs that may be nonspecific or specific.
Nonspecific symptoms (symptoms that also can be seen in other disorders) include:
Symptoms and signs that are specific for liver disease include:
- yellowing of the skin (jaundice) due to the accumulation of bilirubin in the blood,
- itching associated with liver disease, and
- easy bruising due to decreased production of blood clotting factors by the diseased liver.
Severe, advanced liver disease with cirrhosis can produce symptoms and signs related to cirrhosis; these symptoms include:
- fluid accumulation in the legs (edema) and abdomen (ascites, due to increased pressure in the vessels going into the liver),
- mental confusion or coma (from hepatic encephalopathy due to increase in ammonia),
- kidney failure,
- vulnerability to bacterial infections, and
- gastrointestinal bleeding, secondary to varices (enlarged blood vessels in the esophagus or stomach).