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March 21, 2010
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Patient Discussions: Drug-Induced Liver Disease - Describe Your Experience

Drug-Induced Liver Disease - Describe Your Experience

The MedicineNet physician editors ask:

The symptoms of drug-induced liver disease can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

Comment submissions for this question have ended. Patient Discussions FAQs


Related Article: Drug-Induced Liver Disease

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Comment from: TCB, 35-44 Male (Patient)

I was prescribed Diclofenac Sod 75mg and had side affect dark urine and I took about 10 pills. I went for something else now stressed about an elevated bilirubin and I also stop taking Simvastatin. I will change diet and exercise to lower cholesterol. I am still under going tests, but this is not worth the side affects. Published: September 02 ::

Comment from: GIMS, 55-64 Female (Patient)

I started noticing sore nodules in the upper portion of the liver. My urine became dark, and I had decreased urine output. I had been having fatigue for a long time that was diagnosed as anxiety and depression. I am very sensitive to drugs and usually have at least 50% of the side effects of any drug. I am so sad because nobody wanted to listen to my sensitivity to drugs. I refused to take some drugs because I would rather die than live with the side effects. I have ended up with acute liver disease because of some of the drugs I am on. The doctor instantly took me off HCTZ, and I am still worried about Norvasc and Benicar. Published: July 15 ::

Comment from: Leo, 45-54 Male (Patient)

I am 52 with Hepatitis C and my next check up for that is a couple months away. Last month I had a hip resurface and have been on oxycodone. Now, I am not taking oxycodone because of the way it makes me feel and my pain is going away, except I need something to get me thru a nights sleep. My pain level is a lot better. My question is, what pain med over the counter or prescription is best for someone with Hepatitis C. Published: June 29 ::

Comment from: Have FAITH, 35-44 Female (Patient)

I had a few glasses of wine one night, a few days later I became ill, feeling as though I had a flu but with stomach pains. I went to the doctor and she prescribed erythromycin (broad spectrum antibiotic) that night I collapsed on the floor in sever pain. I was taken to the ER where I was diagnosed with stomach pain and given (donnatal). When I returned home my sister (25miles away) called. The ER doctor had contacted my emergency contact as I was on the way home (in even more pain) he had over looked my labs, my alt and slt were elevated (in the thousands) and my pancreas was inflamed, he needed me to come back to the ER immediately. I did and went thru a series of tests and diagnosis on to finally discover that I had autoimmune hepatitis type I (a liver disease where your body attacks your liver) my symptoms were severe pain in my upper right rib cage, extreme fatigue, pale stool, itching, as best I can remember. I was also diagnosed with Hepatitis C and Sjroens syndrome therefore I couldn't be treated for the Hepatitis C. It would make the autoimmune hepatitis worse, so I was put on prednisone and something else but anyway I stopped taking all of it, started eating better and hydrating myself, got pregnant and my levels dropped back to normal. I now have two girls 5 and 2 and so far I feel really good. Let me make it clear that autoimmune hepatitis has a 10 year life expectancy and let me also make it clear that I would not be here today without the power of prayer and that’s why I stopped the medications. It was a walk of faith. Published: June 29 ::

I am a 19 year old female. One day I just started feeling really queasy all the time and not really having much of an appetite, this went on for days and I started getting worried I was pregnant, then I started noticing my urine was a really dark brown, I started getting to the point where I couldn’t keep anything down I then immediately drove myself to the ER. When the ER doctor saw me she then noticed the whites of my eyes were yellow and right there she said hepatitis. After hours of tests and being admitted I was then released the next night, still feeling the same as when I came in they said it was viral it will take awhile to go away. The next day I still felt horrible and couldn’t hold anything down. I called my doctor and he said to go to Dallas so I rushed to Dallas where they had a good liver team and after more and more tests and after being there 3 days I had to get a liver biopsy where I was then diagnosed with autoimmune hepatitis. When I was in high school I was on multiple tetracycline’s for my acne and my doctors realized this is what triggered my liver to do this and now I will be on prednisone and azathioprine for 22 months. So watch out to anybody taking tetracyclines because this could happen. Published: June 29 ::

Comment from: foxisenior2, 45-54 Male (Caregiver)

On Oct. 9, 2008, my 54-year-old son went to the emergency room with severe pain. At first, they thought it was gall stones. Then, after blood work, they discovered he had a leakage in his liver. He died on Dec. 4. He drank a couple of glasses of wine a day and took no drugs. He had ulcers in his bowel and esophagus at age 16 and was treated successfully with Prednisone and never had any more problems until the above. Before he died, he had bad jaundice and terrible itching and some bleeding. Published: March 05 ::

Comment from: 55-64 Female (Patient)

3 weeks ago I collapsed at work, was taken to ER, collapsed again, and diagnosed with seizures. The neurologist put me on Dilantin, and I spent a dreadful week of confusion, weakness, fatigue, loss of appetite, etc. After 1 week of medication I developed a fever and a total body rash and was again admitted to hospital and taken off Dilantin. Now my WBC is 2.5, and all my liver enzymes are elevated. My doctor says I can't return to work until they return to normal, and then she will decide whether to put me on another anticonvulsant. I had a very extended bout of Hepatitis A 30 years ago. Could this be contributing to my reaction to this medication? Published: September 17 ::


Patient Discussions are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified health provider because of something you have read on MedicineNet. The opinions expressed in the comments section are of the author and the author alone. MedicineNet does not endorse any specific product, service or treatment.

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Drug-Induced Liver Disease

What is abdominal pain?

Abdominal pain is pain that is felt in the abdomen. The abdomen is an anatomical area that is bounded by the lower margin of the ribs and diaphragm above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (such as the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity. Organs of the abdomen include the stomach, small intestine, colon, liver, gallbladder, and pancreas.

Occasionally, pain may be felt in the abdomen even though it is arising from organs that are close to, but not within, the abdominal cavity. For example, conditions of the lower lungs, the kidneys, and the uterus or ovaries can cause abdominal pain. On the other hand, it also is possible for pain from organs within the abdomen to be felt outside of the abdomen. For...

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